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CAS 214907-24-1

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trans-2-(4-Fluorophenyl)vinylboronic acid

Description:
Trans-2-(4-Fluorophenyl)vinylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a vinyl group, which is further substituted with a para-fluorophenyl moiety. This compound typically exhibits a planar structure due to the trans configuration, which can influence its reactivity and interactions in chemical reactions, particularly in Suzuki coupling reactions, where boronic acids are commonly utilized as coupling partners. The presence of the fluorine atom enhances the electronic properties of the phenyl ring, potentially increasing the compound's reactivity and solubility in organic solvents. Additionally, boronic acids are known for their ability to form reversible complexes with diols, making them useful in various applications, including drug development and materials science. The compound's solubility, stability, and reactivity can be influenced by factors such as pH and the presence of other functional groups. Overall, trans-2-(4-Fluorophenyl)vinylboronic acid is a valuable intermediate in organic synthesis and medicinal chemistry.
Formula:C8H8BFO2
InChI:InChI=1/C8H8BFO2/c10-8-3-1-7(2-4-8)5-6-9(11)12/h1-6,11-12H/b6-5+
Synonyms:
  • [(E)-2-(4-Fluorophenyl)vinyl]boronic acid
  • Boronic acid, B-[(E)-2-(4-fluorophenyl)ethenyl]-
  • [(E)-2-(4-fluorophenyl)ethenyl]boronic acid
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