CAS 21499-66-1

(1beta,11beta,12alpha,15beta)-1,11,12,14,15-pentahydroxy-13,20-epoxypicras-3-ene-2,16-dione

Description:

The chemical substance known as "(1beta,11beta,12alpha,15beta)-1,11,12,14,15-pentahydroxy-13,20-epoxypicras-3-ene-2,16-dione," with the CAS number 21499-66-1, is a complex organic compound characterized by its polyhydroxylated structure and the presence of an epoxide functional group. This compound belongs to the class of natural products, specifically derived from plants, and is often studied for its potential biological activities, including anti-inflammatory and anticancer properties. The multiple hydroxyl groups contribute to its solubility in polar solvents and may enhance its reactivity in biochemical pathways. The epoxide moiety can participate in various chemical reactions, making it a versatile intermediate in organic synthesis. Additionally, the specific stereochemistry indicated by the nomenclature suggests a unique three-dimensional arrangement that may influence its interaction with biological targets. Overall, this compound exemplifies the intricate chemistry found in natural products and their potential applications in pharmaceuticals and biochemistry.

Formula: C₂₀H₂₆O₉

InChI: InChI=1/C20H26O9/c1-7-4-9(21)13(23)17(2)8(7)5-10-19-6-28-18(3,14(24)11(22)12(17)19)20(19,27)15(25)16(26)29-10/h4,8,10-15,22-25,27H,5-6H2,1-3H3/t8-,10+,11+,12+,13+,14-,15-,17-,18+,19+,20+/m0/s1

InChI key: InChIKey=JBDMZGKDLMGOFR-KQSRGDCESA-N

SMILES: O[C@]12[C@@]34[C@@]([C@]5(C)[C@@](C[C@]3(OC(=O)[C@@H]1O)[H])(C(C)=CC(=O)[C@H]5O)[H])([C@@H](O)[C@H](O)[C@@]2(C)OC4)[H]

Synonyms:

• (1β,11β,12α,15β)-13,20-Epoxy-1,11,12,14,15-pentahydroxypicras-3-ene-2,16-dione
• 5H-3,11cβ-(Epoxymethano)phenanthro[10,1-bc]pyran-5,10(6aβH)-dione, 1,2,3,3a,4,7,7aα,11,11a,11bα-decahydro-1β,2α,3aβ,4β,11β-pentahydroxy-3α,8,11aβ-trimethyl-, (-)-
• Picras-3-ene-2,16-dione, 13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1β,11β,12α,15β)-
• Bruceine D
• NSC 318801
• picras-3-ene-2,16-dione, 13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1beta,11beta,12alpha,15beta)-
• (1beta,11beta,12alpha,15beta)-1,11,12,14,15-Pentahydroxy-13,20-epoxypicras-3-ene-2,16-dione
• BRUCEIND
• Nsc318801
• (1beta,11beta,12alpha,15beta)-13,20-Epoxy-1,11,12,14,15-pentahydroxypicras-3-ene-2,16-dione

Bruceine D

CAS: 21499-66-1

Formula: C₂₀H₂₆O₉

Purity: 95%

Color and Shape: Solid

Molecular weight: 410.4150

Ref: IN-DA003OKX

Bruceine D

CAS: 21499-66-1

Bruceine D

Purity: ≥95%

Molecular weight: 410.42g/mol

Ref: 54-BUP08889

Bruceine D

CAS: 21499-66-1

Formula: C₂₀H₂₆O₉

Molecular weight: 410.42

Ref: 7W-GY3792

Bruceine D

CAS: 21499-66-1

Bruceine D has anti-cancer activity, it inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.Bruceine D may have the potential to be used as a natural viricide, or a lead compound for new viricides.

Formula: C₂₀H₂₆O₉

Purity: 98%

Molecular weight: 410.419

Ref: BP-BP3461

Bruceine D

CAS: 21499-66-1

1.

Formula: C₂₀H₂₆O₉

Purity: 95% - 99.99%

Color and Shape: Solid

Molecular weight: 410.42

Ref: TM-TWS2045

Bruceine D

CAS: 21499-66-1

Bruceine D is a quassinoid compound, which is derived from the seeds of the Brucea javanica plant, known for its medicinal properties. It is predominantly sourced from traditional Chinese medicine where the plant is celebrated for its therapeutic benefits. The mode of action of Bruceine D involves the induction of apoptosis in cancer cells, through the disruption of mitochondrial function and the modulation of multiple cellular signaling pathways.

Formula: C₂₀H₂₆O₉

Purity: Min. 95%

Molecular weight: 410.42 g/mol

Ref: 3D-FB145214

Bruceine D

CAS: 21499-66-1

Purity: 95%

Molecular weight: 410.419

Ref: 10-F979850