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CAS 215178-39-5

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(R)-1-FMOC-3-Pyrrolidinol

Description:
(R)-1-FMOC-3-Pyrrolidinol is a chiral compound commonly used in organic synthesis, particularly in the field of medicinal chemistry and peptide synthesis. It features a pyrrolidine ring, which is a five-membered nitrogen-containing heterocycle, and is protected by a 9-fluorenylmethoxycarbonyl (FMOC) group, a common protecting group for amines. The FMOC group enhances the compound's stability and solubility, facilitating its use in various chemical reactions. As a chiral molecule, (R)-1-FMOC-3-Pyrrolidinol can exist in two enantiomeric forms, with the (R)-configuration being particularly relevant for applications requiring specific stereochemistry. The compound is typically characterized by its molecular weight, solubility in organic solvents, and its reactivity in coupling reactions. Its applications extend to the synthesis of complex organic molecules, including pharmaceuticals, where the control of stereochemistry is crucial for biological activity. Safety data should be consulted for handling and storage, as with any chemical substance.
Formula:C19H19NO3
InChI:InChI=1/C19H19NO3/c21-13-9-10-20(11-13)19(22)23-12-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,13,18,21H,9-12H2/t13-/m1/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=O)N1CC[C@H](C1)O
Synonyms:
  • (R)-1-FMOC-3-hydroxypyrrolidine
  • 9H-fluoren-9-ylmethyl (3R)-3-hydroxypyrrolidine-1-carboxylate
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