CAS 215303-72-3

4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol

Description:

The chemical substance known as 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol, with the CAS number 215303-72-3, is a complex organic compound characterized by its imidazole core, which is a five-membered heterocyclic structure containing nitrogen atoms. This compound features multiple functional groups, including a butynol moiety and a fluorophenyl group, contributing to its potential biological activity. The presence of a pyridine ring enhances its lipophilicity and may influence its interaction with biological targets. The compound's structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific receptors or enzymes. Its unique arrangement of substituents may also impart specific pharmacokinetic properties, such as solubility and stability. As with many synthetic organic compounds, understanding its reactivity, stability under various conditions, and potential toxicity is crucial for its application in research and development.

Formula: C₂₇H₂₄FN₃O

InChI: InChI=1/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2

InChI key: InChIKey=QSUSKMBNZQHHPA-UHFFFAOYSA-N

SMILES: C(CCC1=CC=CC=C1)N2C(=C(N=C2C#CCCO)C3=CC=C(F)C=C3)C=4C=CN=CC4

Synonyms:

• 3-Butyn-1-ol, 4-[4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-
• 4-(4-Fluorophenyl)-2-(4-hydroxy-1-butynyl)-1-(3-Phenylpropyl)-5-(4-Pyridyl)imidazole
• 4-[4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-pyridin-4-yl-1H-imidazol-2-yl]but-3-yn-1-ol
• Jnj 3026582
• Rwj-67657
• 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol
• 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol ISO 9001：2015 REACH
• RWJ-67657; RWJ-67657; RWJ-67657
• RWJ-67657;JNJ-3026582
• CS-1470

RWJ-67657

CAS: 215303-72-3

RWJ-67657

Purity: ≥98%

Molecular weight: 425.5g/mol

Ref: 54-BUP09889

RWJ-67657

CAS: 215303-72-3

Ref: 7W-GW0575

RWJ-67657

CAS: 215303-72-3

RWJ-67657 is a selective oral p38α/β MAPK inhibitor with IC50s of 1/11μM; inactive on p38γ/δ with cardioprotection.

Formula: C₂₇H₂₄FN₃O

Purity: 99.66%

Color and Shape: Solid

Molecular weight: 425.5

Ref: TM-T16812

RWJ-67657

Controlled Product

CAS: 215303-72-3

Formula: C₂₇H₂₄FN₃O

Color and Shape: Neat

Molecular weight: 425.497

Ref: TR-R925200

JNJ 3026582

CAS: 215303-72-3

Inhibits p38α and p38β MAP kinases; cardioprotective; anti-inflammatory

Formula: C₂₇H₂₄FN₃O

Purity: Min. 98 Area-%

Color and Shape: Off-White Powder

Molecular weight: 425.5 g/mol

Ref: 3D-FJ102876