CAS: 215303-72-3 - 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol

Formula: C₂₇H₂₄FN₃O

InChI: InChI=1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2

InChI key: InChIKey=QSUSKMBNZQHHPA-UHFFFAOYSA-N

SMILES: FC1=CC=C(C=C1)C=2N=C(C#CCCO)N(C2C=3C=CN=CC3)CCCC=4C=CC=CC4

Synonyms:

• 3-Butyn-1-ol, 4-[4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-
• 4-(4-Fluorophenyl)-2-(4-hydroxy-1-butynyl)-1-(3-Phenylpropyl)-5-(4-Pyridyl)imidazole
• 4-[4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-pyridin-4-yl-1H-imidazol-2-yl]but-3-yn-1-ol
• Jnj 3026582
• Rwj-67657

RWJ-67657

CAS: 215303-72-3

RWJ-67657

CAS: 215303-72-3

RWJ-67657 is a selective oral p38α/β MAPK inhibitor with IC50s of 1/11μM; inactive on p38γ/δ …

• Formula: C₂₇H₂₄FN₃O
• Purity: 99.66%
• Color and Shape: Solid
• Molecular weight: 425.5

RWJ-67657

CAS: 215303-72-3

• Formula: C₂₇H₂₄FN₃O
• Color and Shape: Neat
• Molecular weight: 425.497

JNJ 3026582

CAS: 215303-72-3

Inhibits p38α and p38β MAP kinases; cardioprotective; anti-inflammatory

• Formula: C₂₇H₂₄FN₃O
• Purity: Min. 98 Area-%
• Color and Shape: Off-White Powder
• Molecular weight: 425.5 g/mol