CAS 21535-47-7

mianserin hydrochloride

Description:

Mianserin hydrochloride is a tetracyclic antidepressant primarily used in the treatment of major depressive disorders. It functions as a noradrenergic and specific serotonergic antidepressant (NaSSA), influencing neurotransmitter systems by antagonizing certain serotonin receptors and enhancing norepinephrine release. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a moderate pH range. Mianserin hydrochloride has a molecular formula that reflects its complex structure, contributing to its pharmacological effects. Its mechanism of action involves the modulation of neurotransmitter levels, which can help alleviate symptoms of depression. Additionally, it may have sedative properties, making it beneficial for patients with insomnia associated with depression. Side effects can include sedation, weight gain, and potential interactions with other medications, necessitating careful monitoring during treatment. As with any antidepressant, it is essential for healthcare providers to evaluate the risk-benefit profile for individual patients.

Formula: C₁₈H₂₁ClN₂

InChI: InChI=1/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H

InChI key: InChIKey=YNPFMWCWRVTGKJ-UHFFFAOYSA-N

SMILES: CN1CC2N(C=3C(CC=4C2=CC=CC4)=CC=CC3)CC1.Cl

Synonyms:

• 2-Methyl-1,2,3,4,10,14B-Hexahydrodibenzo[C,F]Pyrazino[1,2-A]Azepine
• 2-Methyl-1,2,3,4,10,14B-Hexahydrodibenzo[C,F]Pyrazino[1,2-A]Azepine Hydrochloride (1:1)
• 2-Methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride
• Athymil
• Bolvidon
• Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, hydrochloride (1:1)
• Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, monohydrochloride
• Gb 94
• Lantanon
• Mianserin HCl
• Mianserin Hydrocloride
• Mianserine hydrochloride
• NSC 292267
• Norval
• Org GB 94
• Tetramide
• Toluon
• Tolvin
• Tolvon
• Mianserin hydrochloride
• 1,2,3,4,10,14BETA-HEXAHYDRO-2-METHYL-DIBENZO-[C,F]PYRAZINO[1,2-A]AZEPINE HYDROCHLORIDE
• 1,2,3,4,10,14B-HEXAHYDRO-2-METHYL-DIBENZO[C,F]PYRAZINO[1,2-A]AZEPINE HYDROCHLORIDE
• f)pyrazino(1,2-a)azepine,1,2,3,4,10,14b-hexahydro-2-methyl-dibenzo(monohyd
• MIANSERIN HYDROCHLORIDE SEROTONIN ANTAGO NIST
• 1,2,3,4,10,14b-hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepinehydrochlo
• gb94
• MIANSERINE HCL
• orggb94

Mianserin hydrochloride

CAS: 21535-47-7

Mianserin hydrochloride is used as an antidepressant, antagonist, inverse agonist at 5-HT2 serotonin receptors, also blocks the H1 histamine receptor and the 2 adrenoceptor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and

Formula: C₁₈H₂₁ClN₂

Color and Shape: Powder

Molecular weight: 300.83

Ref: 02-J61570

Mianserin Hydrochloride

CAS: 21535-47-7

Color and Shape: Neat

Ref: 61-FOR0147.00

Mianserin Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 21535-47-7

Color and Shape: Single Solution

Ref: 61-AMP0147.00-01

Mianserin.HCl, 1mg/ml in Methanol (as free base)

CAS: 21535-47-7

Color and Shape: Single Solution

Ref: LP-MSR-1438-HC-1LM

Mianserin hydrochloride

CAS: 21535-47-7

Mianserin hydrochloride

Formula: C₁₈H₂₀N₂HCl

Purity: 99.4%

Color and Shape: Off White Solid

Molecular weight: 300.13933

Ref: 47-252

MIANSERIN HYDROCHLORIDE CRS

CAS: 21535-47-7

MIANSERIN HYDROCHLORIDE CRS

Formula: C₁₈H₂₁ClN₂

Color and Shape: Crystalline Powder. White. Crystals. Powder.

Molecular weight: 300.8257

Ref: 41-M1875000

MIANSERIN FOR SYSTEM SUITABILITY CRS

CAS: 21535-47-7

MIANSERIN FOR SYSTEM SUITABILITY CRS

Formula: C₁₈H₂₁ClN₂

Molecular weight: 300.8257

Ref: 41-Y0000862

Mianserin hydrochloride

CAS: 21535-47-7

Mianserin HCl (Org GB 94): a tetracyclic antidepressant; blocks alpha-adrenergic, H1, serotonin receptors; may induce drowsiness, hematological issues.

Formula: C₁₈H₂₁ClN₂

Purity: 99.63% - 99.82%

Color and Shape: White And Film Coated Tablet And Seem To Be White Or White-Like After Removing It'S Film Coated

Molecular weight: 300.83

Ref: TM-T0783

Mianserin (hydrochloride)

CAS: 21535-47-7

Formula: C₁₈H₂₁ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 300.8257

Ref: IN-DA003273

Mianserin Hydrocloride

CAS: 21535-47-7

Mianserin Hydrocloride

Purity: 98%

Molecular weight: 300.83g/mol

Ref: 54-OR1027121

Mianserin hydrochloride

CAS: 21535-47-7

Mianserin hydrochloride

Purity: ≥98%

Molecular weight: 300.83g/mol

Ref: 54-BUP17047

Mianserin HCl

CAS: 21535-47-7

Formula: C₁₈H₂₀N₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 264.37 36.46

Ref: 4Z-M-094

Mianserine hydrochloride

CAS: 21535-47-7

Formula: C₁₈H₂₀N₂·HCl

Molecular weight: 300.83

Ref: 7W-GP8102

Mianserin Hydrochloride

CAS: 21535-47-7, 24219-97-4

Formula: C₁₈H₂₀N₂·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 300.83

Ref: 3B-M2623

Mianserin Hydrochloride

Controlled Product

CAS: 21535-47-7

Formula: C₁₈H₂₀N₂·ClH

Color and Shape: Neat

Molecular weight: 300.83

Ref: 86-MM0147.00

Mianserin.HCl

CAS: 21535-47-7

Color and Shape: Neat

Ref: LP-MSR-1438-HC-10

Mianserin Hydrochloride

CAS: 21535-47-7

Applications Serotonin receptor antagonist. Antidepressant.
References Saxena, et al.: Eur. J. Pharmacol., 13, 295 (1971), Brogden, R.N., et al.: Drugs, 16, 273 (1978), Alexander, B.S., et al.: J. Pharm. Pharmacol., 39, 664 (1987)

Formula: C₁₈H₂₀N₂·ClH

Color and Shape: Neat

Molecular weight: 300.83

Ref: TR-M341500

Mianserin HCl - Bio-X ™

Controlled Product

CAS: 21535-47-7

Mianserin is a tetracyclic antidepressant drug that has antihistaminic and hypnosedative properties. It is used to treat depression in adults and children, as well as other disorders such as chronic pain and irritable bowel syndrome. This drug’s mechanism of action is not fully understood but is said to block alpha-adrenergic, histamine H1 and serotonin receptors.

Formula: C₁₈H₂₀N₂•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 300.83 g/mol

Ref: 3D-BM166416

Mianserine HCl

Controlled Product

CAS: 21535-47-7

Serotonin 5-HT and histamine H1 receptor antagonist; anti-depressant

Formula: C₁₈H₂₁ClN₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 300.83 g/mol

Ref: 3D-FM25996