CAS 2157462-42-3

Paclitaxel EP Impurity I (Paclitaxel 10,13-Bis Side Chain)

CAS: 2157462-42-3

Formula: C₆₁H₆₂N₂O₁₆

Color and Shape: White To Off-White Solid

Molecular weight: 1079.17

Ref: 4Z-P-2817

10-O-[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel

Controlled Product

CAS: 2157462-42-3

Applications 10-O-[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel is an impurity in the synthesis of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma.
References Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984), Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984), Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995), Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002), Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004),

Formula: C₆₁H₆₂N₂O₁₆

Color and Shape: White To Off-White

Molecular weight: 1079.15

Ref: TR-B207800

Paclitaxel EP Impurity I

CAS: 2157462-42-3

Formula: C₆₁H₆₂N₂O₁₆

Molecular weight: 1079.17

Ref: ST-EA-CP-P36186