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CAS 215777-46-1

:

7-36-Glucagon-likepeptide I (human), 8-L-serine-36-L-argininamide-

Description:
7-36-Glucagon-like peptide I (human), 8-L-serine-36-L-argininamide, commonly referred to as GLP-1, is a peptide hormone that plays a crucial role in glucose metabolism and appetite regulation. It is derived from the proglucagon gene and is primarily secreted by the intestinal L-cells in response to food intake. This peptide consists of 36 amino acids and is characterized by its ability to stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, thereby helping to lower blood glucose levels. Additionally, GLP-1 inhibits glucagon release, slows gastric emptying, and promotes satiety, making it a target for diabetes treatment and obesity management. The CAS number 215777-46-1 identifies this specific peptide, which is often used in research and therapeutic applications. Its stability and activity can be influenced by modifications to its structure, such as the addition of amino acids like L-serine and L-arginine, which can enhance its pharmacological properties. Overall, GLP-1 is a vital component in the regulation of metabolic processes and has significant implications in the treatment of type 2 diabetes.
Formula:C149H226N40O46
Synonyms:
  • 7-36-Glucagon-likepeptide 1 (Octodon degus), 8-L-serine-36-L-argininamide- (9CI)
  • L-Argininamide, L-histidyl-L-seryl-L-a-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-a-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-a-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-a-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-
  • (Ser79)-Proglucagon (78-107) Amide (Human, Bovine, Guinea Pig, Mouse, Rat) Trifluoroacetate Salt
  • 22: PN:WO0155213 SEQID: 22 claimed sequence
  • 7-36-Glucagon-like peptide I (human), 8-L-serine-36-L-argininamide-
  • 8-L-Serine-36-L-argininamide-7-36-glucagon-like peptide I (human)
  • (SER99)-PREPROGLUCAGON (98-127) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
  • (Ser8)-Glucagon-LikePeptide1(7-36)amide
  • (SER8)-GLP-1 (7-36) AMIDE (HUMAN)
  • (Ser?)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)
  • See more synonyms
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Found 2 products.
  • (Ser⁸)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)
    Bachem
    + Info

    (Ser⁸)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)

    CAS:
    The replacement of alanine by serine significantly improved the plasma stability of GLP-1 (7-36) amide against DPP IV without impairing its insulinotropic activity. This may indicate that this modification could improve the potential of GLP-1 in the treatment of type-II diabetes.
    Formula:C149H226N40O46
    Purity:95.2%
    Color and Shape:White Powder
    Molecular weight:3313.68

    Ref: 01-4029130

    1mg
    555.00€
    0.5mg
    314.00€
  • (Ser8)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt
    Biosynth
    + Info

    (Ser8)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt

    CAS:
    <p>Please enquire for more information about (Ser8)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:C149H226N40O46
    Purity:Min. 95%
    Molecular weight:3,313.63 g/mol

    Ref: 3D-FS109310

    1mg
    860.00€
    2mg
    1,323.00€
    5mg
    2,806.00€