CAS 215803-78-4

SB 277011

Description:

SB 277011, with the CAS number 215803-78-4, is a chemical compound that has been studied primarily for its potential applications in the field of medicinal chemistry, particularly as a selective inhibitor of certain biological pathways. It is characterized by its specific molecular structure, which includes various functional groups that contribute to its biological activity. The compound has been investigated for its effects on certain receptors or enzymes, making it of interest in drug development, especially in the context of treating diseases where modulation of these targets is beneficial. Its solubility, stability, and pharmacokinetic properties are also key characteristics that influence its efficacy and safety profile. As with many compounds in drug discovery, the understanding of SB 277011's mechanism of action, along with its potential side effects and interactions with other substances, is crucial for evaluating its therapeutic potential. Further research and clinical studies are typically required to fully elucidate its characteristics and applications in medicine.

Formula: C₂₈H₃₀N₄O

InChI: InChI=1/C28H30N4O/c29-18-21-5-8-23-19-32(16-13-22(23)17-21)15-12-20-6-9-24(10-7-20)31-28(33)26-11-14-30-27-4-2-1-3-25(26)27/h1-5,8,11,14,17,20,24H,6-7,9-10,12-13,15-16,19H2,(H,31,33)/t20-,24-

InChI key: InChIKey=OLWRVVHPJFLNPW-LSNLESRRNA-N

SMILES: C(N[C@@H]1CC[C@@H](CCN2CC=3C(CC2)=CC(C#N)=CC3)CC1)(=O)C=4C5=C(N=CC4)C=CC=C5

Synonyms:

• 4-Quinolinecarboxamide, N-[trans-4-[2-(6-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-
• SB 277011
• SB 277011A
• N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide
• SB 277211

N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide

CAS: 215803-78-4

Formula: C₂₈H₃₀N₄O

Purity: 95%

Molecular weight: 438.564

Ref: IN-DA00BF4J

SB-277011

CAS: 215803-78-4

SB-277011

Purity: ≥98%

Molecular weight: 438.56g/mol

Ref: 54-BUP11473

SB-277011

CAS: 215803-78-4

SB-277011 is a dopamine receptor antagonist that binds to the 5-HT2A and D receptors. SB-277011 has been shown to be effective in treating symptoms of Parkinson's disease. It has also been shown to inhibit the inflammatory response in an animal model of bowel disease. The drug is still undergoing clinical trials for its effectiveness in treating other conditions, including Parkinson's disease and inflammatory bowel disease.

Formula: C₂₈H₃₀N₄O

Purity: Min. 95%

Molecular weight: 438.56 g/mol

Ref: 3D-QIA80378

SB-277011

CAS: 215803-78-4

SB-277011A: dopamine D3 antagonist, pKi 8.0 (D3), 6.0 (D2), 5.0 (5-HT1D), <5.2 (5-HT1B).

Formula: C₂₈H₃₀N₄O

Purity: 99.39%

Color and Shape: Solid

Molecular weight: 438.56

Ref: TM-T12861