CAS 216064-36-7

β-Pompilidotoxin

CAS: 216064-36-7

β-Pompilidotoxin is a neurotoxin that is found in the venom of the scorpion Pompilus. It binds to the ryanodine receptor, which is a type of calcium channel protein that regulates intracellular calcium levels. β-Pompilidotoxin blocks the release of calcium from the sarcoplasmic reticulum and inhibits the entry of calcium into cells by blocking voltage-gated sodium channels. It has been shown to be cytotoxic to ventricular myocytes and cerebellar purkinje neurons. β-Pompilidotoxin also has a physiological function in regulating glomerular filtration rate and preventing accumulation of intracellular calcium, which can lead to overload.

Formula: C₇₁H₁₂₄N₂₂O₁₇

Purity: Min. 95%

Molecular weight: 1,557.9 g/mol

Ref: 3D-RIA06436