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CAS 2162-74-5

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bis(2,6-diisopropylphenyl)carbodiimide

Description:
Bis(2,6-diisopropylphenyl)carbodiimide, commonly referred to as DIC, is a chemical compound characterized by its unique structure, which features two 2,6-diisopropylphenyl groups attached to a central carbodiimide functional group. This compound is typically a white to pale yellow solid at room temperature and is known for its role as a coupling agent in organic synthesis, particularly in peptide synthesis and the formation of amide bonds. DIC is valued for its ability to activate carboxylic acids, facilitating their reaction with amines to form amides. It is relatively stable under standard conditions but can decompose upon exposure to moisture or in the presence of strong acids or bases. The compound is soluble in organic solvents such as dichloromethane and acetonitrile, making it versatile for various synthetic applications. Safety precautions should be taken when handling DIC, as it can be irritating to the skin and eyes, and proper ventilation is recommended due to its potential toxicity.
Formula:C25H34N2
InChI:InChI=1/C25H34N2/c1-16(2)20-11-9-12-21(17(3)4)24(20)26-15-27-25-22(18(5)6)13-10-14-23(25)19(7)8/h9-14,16-19H,1-8H3
InChI key:InChIKey=XLDBGFGREOMWSL-UHFFFAOYSA-N
SMILES:N(=C=NC1=C(C(C)C)C=CC=C1C(C)C)C2=C(C(C)C)C=CC=C2C(C)C
Synonyms:
  • 2,2′,6,6′-Tetraisopropyldiphenylcarbodiimide
  • Additin RC 8500
  • Benzenamine, N,N′-methanetetraylbis[2,6-bis(1-methylethyl)-
  • Bis(o,o′-diisopropylphenyl)carbodiimide
  • Carbo D
  • Carbodiimide, bis(2,6-diisopropylphenyl)-
  • Chinox SA 1
  • En 160
  • Hycasyl 1001
  • N,N'-bis[2,6-di(propan-2-yl)phenyl]carbodiimide
  • See more synonyms
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