CAS 2163060-83-9

WY-135

CAS: 2163060-83-9

Wy-135 is a potential drug that has shown inhibition of cyclin-dependent kinases. It has been shown to inhibit G1 phase cell cycle progression and induce apoptosis in a dose-dependent manner. Wy-135 has also been shown to inhibit the growth of cancer cells in culture. This compound may be useful as an anti-cancer agent and chemotherapeutic drug. Wy-135 inhibits cellular proliferation and induces apoptosis by inhibiting protein synthesis, DNA replication, and enzyme activity. The cocrystal structure of Wy-135 with cyclin was determined and its inhibitory activities were analyzed by cycle analysis. Wy-135's effects on cancer cells are due to its ability to inhibit the enzymatic activities involved in cell division, including protein synthesis and DNA replication.

Formula: C₂₈H₃₄ClN₉O₃S

Purity: Min. 95%

Molecular weight: 612.1 g/mol

Ref: 3D-NLD06083

WY-135

CAS: 2163060-83-9

WY-135 is a dual inhibitor of ALK and ROS1 (IC50 of 1.4 nM and 1.1 nM, respectively).

Formula: C₂₈H₃₄ClN₉O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 612.15

Ref: TM-T13351