CAS 2166-34-9

5,6-Diphenyl-3(2H)-pyridazinone

Description:

5,6-Diphenyl-3(2H)-pyridazinone, with the CAS number 2166-34-9, is a heterocyclic organic compound characterized by its pyridazinone structure, which features a pyridazine ring fused with a carbonyl group. This compound typically exhibits a pale yellow to off-white crystalline appearance. It is known for its potential biological activities, including anti-inflammatory and analgesic properties, making it of interest in pharmaceutical research. The presence of two phenyl groups at the 5 and 6 positions of the pyridazinone ring contributes to its lipophilicity, which can influence its bioavailability and interaction with biological targets. Additionally, the compound may exhibit various reactivity patterns typical of pyridazinones, such as undergoing nucleophilic substitutions or forming coordination complexes with metal ions. Its solubility can vary depending on the solvent, and it may be stable under standard laboratory conditions. Overall, 5,6-Diphenyl-3(2H)-pyridazinone represents a versatile scaffold for further chemical modifications and applications in medicinal chemistry.

Formula: C₁₆H₁₂N₂O

InChI: InChI=1S/C16H12N2O/c19-15-11-14(12-7-3-1-4-8-12)16(18-17-15)13-9-5-2-6-10-13/h1-11H,(H,17,19)

InChI key: InChIKey=IXUSMEFHLXSTAV-UHFFFAOYSA-N

SMILES: O=C1C=C(C(=NN1)C2=CC=CC=C2)C3=CC=CC=C3

Synonyms:

• 3(2H)-pyridazinone, 5,6-diphenyl-
• 3-Pyridazinol, 5,6-Diphenyl-
• 5,6-Diphenyl-3(2H)-pyridazinone
• 5,6-Diphenylpyridazin-3-Ol
• 5,6-Diphenylpyridazin-3(2H)-one
• 5,6-Diphenylpyridazin-3(2H)-one

5,6-Diphenyl-2,3-dihydropyridazin-3-one

CAS: 2166-34-9

Vinblastine is a cytotoxic drug that inhibits the growth of cells by binding to DNA. It is used in the treatment of cancers and other diseases such as Hodgkin's disease. Vinblastine binds to the hepg2 cell, an enzyme involved in RNA synthesis. This binding prevents guanosine from functioning as a building block for RNA synthesis, leading to decreased protein synthesis and cell death. The kinetic data obtained from this study was used to calculate the molecular weight of vinblastine, which was found to be 594 Da. Vinblastine has been shown to inhibit the growth of bacteria including typhimurium and subtilis, and it also has some effect against chlorinated hydrocarbons.

Formula: C₁₆H₁₂N₂O

Purity: Min. 95%

Molecular weight: 248.28 g/mol

Ref: 3D-CAA16634