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CAS 21679-12-9

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2'-deoxy-2-fluoroadenosine

Description:
2'-Deoxy-2-fluoroadenosine is a modified nucleoside that features a fluorine atom substituted at the 2' position of the ribose sugar moiety, replacing the hydroxyl group typically found in adenosine. This modification imparts unique biochemical properties, making it of interest in various fields, including medicinal chemistry and molecular biology. The presence of the fluorine atom enhances the stability of the nucleoside against enzymatic degradation, which can be advantageous in therapeutic applications. Additionally, 2'-deoxy-2-fluoroadenosine can act as a substrate for certain enzymes, potentially influencing nucleic acid synthesis and cellular processes. Its structural characteristics allow it to participate in hydrogen bonding and base pairing, similar to natural nucleosides, while also providing insights into the mechanisms of nucleic acid interactions. The compound is often studied for its potential roles in antiviral and anticancer therapies, as well as in the development of nucleoside analogs that can modulate biological pathways.
Formula:C10H12FN5O3
InChI:InChI=1/C10H12FN5O3/c11-10-14-8(12)7-9(15-10)16(3-13-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,14,15)/t4-,5+,6+/m0/s1
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