CAS 2169-64-4

Azaribine

Description:

Azaribine, with the CAS number 2169-64-4, is a chemical compound that belongs to the class of azole derivatives. It is primarily known for its application in the field of medicinal chemistry, particularly as an antiviral agent. Azaribine exhibits a unique structure that contributes to its biological activity, which includes the inhibition of viral replication. The compound is characterized by its ability to interfere with nucleic acid synthesis, making it a potential therapeutic option for certain viral infections. In terms of physical properties, Azaribine is typically a solid at room temperature and may exhibit solubility in various organic solvents. Its stability and reactivity can vary depending on environmental conditions such as pH and temperature. As with many chemical substances, safety precautions should be taken when handling Azaribine, as it may pose health risks if ingested or improperly managed. Overall, Azaribine represents a significant compound in the study of antiviral therapies and continues to be of interest in pharmaceutical research.

Formula: C₁₄H₁₇N₃O₉

InChI: InChI=1S/C14H17N3O9/c1-6(18)23-5-9-11(24-7(2)19)12(25-8(3)20)13(26-9)17-14(22)16-10(21)4-15-17/h4,9,11-13H,5H2,1-3H3,(H,16,21,22)/t9-,11-,12-,13-/m1/s1

InChI key: InChIKey=QQOBRRFOVWGIMD-OJAKKHQRSA-N

SMILES: O(C(C)=O)[C@H]1[C@@H](O[C@H](COC(C)=O)[C@H]1OC(C)=O)N2C(=O)NC(=O)C=N2

Synonyms:

• 1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2,3,5-tri-O-acetyl-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-
• 2,3,5-Tri-O-acetyl-6-azauridine
• 2-(2,3,5-Tri-O-acetyl-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
• 2-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
• 2-(2,3,5-tri-O-acetylpentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
• 2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 2,3,5-triacetate
• 6-Aza-2′,3′,5′-tri-O-acetyluridine
• 6-Azauridine triacetate
• Azaribin
• Azaribine
• Cb 304
• NSC 67239
• Triazure
• as-Triazine-3,5(2H,4H)-dione, 2-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 2′,3′,5′-triacetate
• 2-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
• as-Triazine-3,5(2H,4H)-dione, 2-β-D-ribofuranosyl-, 2′,3′,5′-triacetate

Azaribine

CAS: 2169-64-4

Azaribine

Purity: ≥98%

Molecular weight: 371.3g/mol

Ref: 54-BUP10532

Azaribine

CAS: 2169-64-4

Azaribine (2;,3;,5;-Tri-O-acetyl-6-azauridine) is an OMPD inhibitor with antiviral activity and has been used in the study of Zika virus (ZIKV) infections.

Formula: C₁₄H₁₇N₃O₉

Purity: 98.6% - 99.58%

Color and Shape: Solid

Molecular weight: 371.30

Ref: TM-T25130

2',3',5'-Tri-O-acetyl-6-azauridine

CAS: 2169-64-4

2',3',5'-Tri-O-acetyl-6-azauridine is a nucleoside analog for research purposes. The replacement of a carbon atom with a nitrogen atom on the uracil base affects how the molecule interacts with cellular processes. It has the potential to interfere with normal metabolic processes within cells, particularly those related to RNA synthesis. Due to its ability to disrupt cell growth, it could be studied for any potential antiviral or antitumor properties.

Formula: C₁₄H₁₇N₃O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 371.3 g/mol

Ref: 3D-NT32421

6-Azauridine Triacetate

Controlled Product

CAS: 2169-64-4

Applications 6-Azauridine Triacetate is used in the preparation of potential 3-deazauridine and 6-azauridine prodrugs through enzymic alcoholysis, active antiviral compound against new york isolate of West Nile virus.
References Zinni, M. A., et al.: Journal of Molecular Catalysis B: Enzymatic, J. Mol., 47, 86 (2007); Morrey, J. D., et al.: Antiviral Res., 55, 107 (2002)

Formula: C₁₄H₁₇N₃O₉

Color and Shape: Neat

Molecular weight: 371.3

Ref: TR-A805110