CAS 21691-41-8

N-[(benzyloxy)carbonyl]-N-methylalanine

Description:

N-[(benzyloxy)carbonyl]-N-methylalanine, also known by its CAS number 21691-41-8, is an amino acid derivative characterized by the presence of a benzyloxycarbonyl (Z) protecting group on the amino group and a methyl group on the alpha carbon. This compound features a chiral center, which contributes to its potential stereochemical diversity. It is typically used in peptide synthesis and as an intermediate in organic synthesis due to its ability to protect the amino group while allowing for further functionalization. The benzyloxycarbonyl group enhances the stability of the amino acid during reactions and can be removed under specific conditions to yield the free amino acid. The compound is generally soluble in organic solvents and exhibits moderate stability under standard laboratory conditions. Its properties make it valuable in the fields of medicinal chemistry and biochemistry, particularly in the design and synthesis of peptide-based therapeutics.

Formula: C₁₂H₁₅NO₄

InChI: InChI=1/C12H15NO4/c1-9(11(14)15)13(2)12(16)17-8-10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3,(H,14,15)

SMILES: CC(C(=O)O)N(C)C(=O)OCc1ccccc1

Synonyms:

• Cbz-N-methyl-L-alanine
• Z-N-Me-Ala-OH
• Z-MeAla-OH

Z-MeAla-OH

CAS: 21691-41-8

Formula: C₁₂H₁₅NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 237.2518

Ref: IN-DA00BDH7

Z-MeAla-OH

CAS: 21691-41-8

Z-MeAla-OH

Purity: 98%

Molecular weight: 237.25g/mol

Ref: 54-OR1015457

Z-N-Me-Ala-OH

CAS: 21691-41-8

Formula: C₁₂H₁₅NO₄

Purity: ≥ 98.0%

Color and Shape: White or almost white powder

Molecular weight: 237.25

Ref: 7W-GM4539

Z-N-Me-Ala-OH

CAS: 21691-41-8

M06158 - Z-N-Me-Ala-OH

Formula: C₁₂H₁₅NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 237.255

Ref: 10-M06158

Z-MeAla-OH-13CD3

Controlled Product

CAS: 21691-41-8

Applications Z-MeAla-OH-13CD3 is an intermediate used in the synthesis of Mertansine-13CD3 (M257802), which is the isotope labelled analog of Mertansine (M257800); a cytotoxic agent used as the cytotoxic component in antibody-drug conjugates.
References Erickson, H., et al.: Cancer Res., 66, 4426 (2006); Kellogg, B., et al.: Bioconjugate Chem., 22, 717 (2011)

Formula: CC₁₁D₃H₁₂NO₄

Color and Shape: Neat

Molecular weight: 241.263

Ref: TR-M335012