CAS 216976-76-0

3'-Azido-3'-deoxy-β-L-adenosine

CAS: 216976-76-0

3'-Azido-3'-deoxy-beta-L-adenosine is a Nucleoside Derivative - L-nucleoside, Azido-nucleoside.

Formula: C₁₀H₁₂N₈O₃

Color and Shape: Solid

Molecular weight: 292.25

Ref: TM-TNU0351

3’-Azido-3’-deoxy-b-L-adenosine

CAS: 216976-76-0

3’-Azido-3’-deoxy-b-L-adenosine is a novel nucleoside that has been synthesized to be used as an antiviral agent. It is phosphorylated, which allows it to be activated by adenosine kinase, and is thus able to inhibit viral replication and spread. 3’-Azido-3’-deoxy-b-L-adenosine is effective against various viruses, including HIV, herpes simplex virus type 1 (HSV1), and hepatitis C virus (HCV). This nucleoside also has anticancer activity due to its ability to inhibit the synthesis of DNA and RNA. It has been modified from the natural nucleosides with the addition of a 2′,3′ azido group at the 3 position on the ribose sugar. The modification prevents viral resistance because it does not require activation by cellular kinases or phosphorylation in order to be active.

Purity: Min. 95%

Ref: 3D-NA163026