CAS 217082-58-1

L-Phenylalanine,L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-

Description:

The chemical substance with the name "L-Phenylalanine, L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-" and CAS number 217082-58-1 is a synthetic peptide composed of multiple amino acids. This compound features a sequence that includes essential and non-essential amino acids, which are the building blocks of proteins. Its structure suggests potential biological activity, possibly related to signaling or regulatory functions in biological systems. Peptides like this one can exhibit various properties, including solubility in water, stability under physiological conditions, and the ability to interact with specific receptors or enzymes. The presence of multiple amino acids in the sequence may also influence its conformation and, consequently, its biological activity. Such compounds are often studied for their potential therapeutic applications, including roles in nutrition, metabolism, and as precursors for larger protein structures. However, specific characteristics such as melting point, solubility, and biological activity would require empirical data for precise determination.

Formula: C₆₉H₁₁₁N₂₃O₁₆S

Synonyms:

• 15: PN: WO2004081198 SEQID: 4 claimedsequence
• 1: PN: WO2009033784 PAGE: 98 claimed protein
• 2: PN:WO2009033819 PAGE: 103 claimed protein
• 65-77-Apelin (Mus musculus)
• 65-77-Apelin, prepro-
• Apelin-13
• Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

Apelin-13, Human, Bovine

CAS: 217082-58-1

For cellular and molecular biology applications

Color and Shape: White, Lyophilized Powder

Ref: 02-J66620

Apelin-13 (human, bovine, mouse, rat)

CAS: 217082-58-1

Apelin-13, generated from apelin-36, is an endogenous peptide ligand for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with a median effective concentration (EC₅₀) value of 0.37 nM. In a study of Valle et al. chronic central administration of apelin-13 over 10 days increased food intake, body weight, locomotor activity and body temperature in C57BL/6 mice.

Formula: C₆₉H₁₁₁N₂₃O₁₆S

Purity: 98.1%

Color and Shape: White White Lyophilisate

Molecular weight: 1550.85

Ref: 01-4029109

Apelin-13

CAS: 217082-58-1

Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor

Formula: C₆₉H₁₁₁N₂₃O₁₆S

Purity: 96.81%

Color and Shape: Solid

Molecular weight: 1550.83

Ref: TM-T7656

Apelin-13

CAS: 217082-58-1

Formula: C₆₉H₁₁₁N₂₃O₁₆S

Purity: 95%

Color and Shape: Solid

Molecular weight: 1550.8291

Ref: IN-DA0037K4

Apelin-13

CAS: 217082-58-1

Formula: C₆₉H₁₁₁N₂₃O₁₆S

Purity: ≥ 97.0%

Color and Shape: White powder or solid

Molecular weight: 1550.8

Ref: 7W-GM7396

Apelin-13 (human, bovine, mouse, rat)

CAS: 217082-58-1

Apelin-13 is a peptide hormone that regulates the release of insulin and has been shown to play a role in metabolic disorders. It is a member of the apelin family, which includes human, bovine, and mouse apelin-12, as well as rat apelin-13. Apelin-13 binds to ATP-binding cassette transporter type 2 (ABC2) and increases autophagy by increasing its expression. Apelin-13 also induces mitochondrial membrane potential changes and neuronal death. These effects are mediated by an increase in reactive oxygen species production. Apelin-13 has been shown to be effective in treating experimental models of Parkinson's disease and Alzheimer's disease.

Formula: C₆₉H₁₁₁N₂₃O₁₆S

Purity: Min. 95%

Molecular weight: 1,550.83 g/mol

Ref: 3D-FA109297