CAS 217087-09-7: Esomeprazole magnesium trihydrate

Description: Esomeprazole magnesium trihydrate is a proton pump inhibitor primarily used to treat gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid production. It is the magnesium salt of the S-enantiomer of omeprazole, which enhances its bioavailability and therapeutic efficacy. This compound is characterized by its white to off-white crystalline appearance and is soluble in water, which facilitates its absorption in the gastrointestinal tract. The trihydrate form indicates that it contains three molecules of water, contributing to its stability and solubility. Esomeprazole magnesium trihydrate works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to a decrease in gastric acid secretion. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations typically occurring within a few hours after administration. Common side effects may include headache, nausea, and abdominal pain, while long-term use has been associated with potential risks such as vitamin B12 deficiency and gastrointestinal infections. Overall, esomeprazole magnesium trihydrate is an effective medication for managing acid-related disorders.

Formula: C₃₄H₄₂MgN₆O₉S₂

InChI: InChI=1/2C17H18N3O3S.Mg.3H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;;;/h2*5-8H,9H2,1-4H3;;3*1H2/q2*-1;+2;;;

Synonyms:

• Bis(5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzylimidazole-1-yl) magnesium trihydrate
• Magnesium 5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide Hydrate (1:2:3)

Esomeprazole magnesium trihydrate CRS

CAS: 217087-09-7

• Formula: C₃₄H₃₆MgN₆O₆S₂
• Color and Shape: White. Whitish. Powder.
• Molecular weight: 713.1212

Esomeprazole Magnesium

CAS: 217087-09-7

Compounds containing an unfused pyridine ring in the structure, nesoi

• Formula: C₃₄H₃₆MgN₆O₆S₂· 3H₂O
• Color and Shape: White Powder
• Molecular weight: 712.19882

Esomeprazole Magnesium trihydrate

CAS: 217087-09-7

• Formula: C₃₄H₄₂MgN₆O₉S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 767.1670800000004

Esomeprazole Magnesium

CAS: 217087-09-7

• Molecular weight: 767.17g/mol

Esomeprazole Magnesium Trihydrate

CAS: 217087-09-7

• Formula: C₁₇H₁₈N₃O₃S·MgH₂O
• Color and Shape: Neat
• Molecular weight: 767.17

Esomeprazole magnesium trihydrate

CAS: 217087-09-7

• Formula: C₁₇H₁₈N₃O₃S·MgH₂O
• Color and Shape: Neat
• Molecular weight: 767.17

Esomeprazole Magnesium trihydrate

CAS: 217087-09-7

Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term …

• Formula: C₃₄H₄₂MgN₆O₉S₂
• Purity: 98.52%
• Color and Shape: Off-White Powder
• Molecular weight: 767.17

Esomeprazole Magnesium

CAS: 217087-09-7

Stability Hygroscopic Applications S-Form of Omeprazole. Gastric proton-pump inhibitor. References Stenhoff, H., et al.: J. …

• Formula: C₁₇H₁₈N₃O₃S·MgH₂O
• Color and Shape: Neat
• Molecular weight: 767.17

Esomeprazole magnesium trihydrate

CAS: 217087-09-7

Proton pump inhibitor

• Formula: C₃₄H₃₆MgN₆O₆S₂·3H₂O
• Purity: Min. 95%
• Color and Shape: Beige Powder
• Molecular weight: 767.17 g/mol

Esomeprazole magnesium trihydrate - Bio-X ™

CAS: 217087-09-7

Esomeprazole is an anti-ulcer drug that is used in the treatment of GERD and to …

• Formula: C₃₄H₃₆MgN₆O₆S₂·3H₂O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 767.17 g/mol