CAS 21715-46-8

Etifoxine

Description:

Etifoxine is a chemical compound classified as an anxiolytic agent, primarily used in the treatment of anxiety disorders. It is known for its unique mechanism of action, which involves modulation of the GABAergic system, enhancing the effects of GABA, a key inhibitory neurotransmitter in the brain. Unlike traditional benzodiazepines, etifoxine has a lower potential for dependence and withdrawal symptoms, making it a favorable option for long-term management of anxiety. The compound exhibits anti-inflammatory properties and may also promote neuroprotection, contributing to its therapeutic effects. Etifoxine is typically administered orally and has a relatively rapid onset of action. Its pharmacokinetics suggest good absorption and distribution in the body, although specific details regarding its metabolism and excretion may vary. Overall, etifoxine represents a distinct approach to anxiety treatment, combining anxiolytic effects with additional benefits that may enhance patient outcomes.

Formula: C₁₇H₁₇ClN₂O

InChI: InChI=1S/C17H17ClN2O/c1-3-19-16-20-15-10-9-13(18)11-14(15)17(2,21-16)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3,(H,19,20)

InChI key: InChIKey=IBYCYJFUEJQSMK-UHFFFAOYSA-N

SMILES: CC1(C=2C(N=C(NCC)O1)=CC=C(Cl)C2)C3=CC=CC=C3

Synonyms:

• 2-Aethylamino-6-chlor-4-methyl-4-phenyl-4H-3,1-benzoxazin
• 2-Aethylamino-6-chlor-4-methyl-4-phenyl-4H-3,1-benzoxazin [German]
• 2-Ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine
• 4H-3,1-Benzoxazin-2-amine, 6-chloro-N-ethyl-4-methyl-4-phenyl-
• 4H-3,1-Benzoxazin-2-amine, 6-chloro-N-ethyl-4-methyl-4-phenyl- (9CI)
• 4H-3,1-Benzoxazine, 6-chloro-2-ethylamino-4-methyl-4-phenyl-
• 6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine
• 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine
• Brn 0548223
• Etafenoxine
• Etifoxin
• Etifoxina
• Etifoxina [INN-Spanish]
• Etifoxina [Spanish]
• Etifoxine [INN:DCF]
• Etifoxinum
• Etifoxinum [INN-Latin]
• Etifoxinum [Latin]
• Hoe 36-801
• Hoe 36801
• Unii-X24X82Mx4X

Etifoxine

CAS: 21715-46-8

Formula: C₁₇H₁₇ClN₂O

Purity: %

Color and Shape: Solid

Molecular weight: 300.7827

Ref: IN-DA00BEBA

Etifoxine

CAS: 21715-46-8

Formula: C₁₇H₁₇ClN₂O

Color and Shape: White To Off-White Solid

Molecular weight: 300.79

Ref: 4Z-E-391

Etifoxine-13C-d3

CAS: 21715-46-8

Formula: C₁₆₁₃CH₁₄D₃ClN₂O

Color and Shape: White To Off-White Solid

Molecular weight: 304.80

Ref: 4Z-E-397

Etifoxine

CAS: 21715-46-8

Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.

Formula: C₁₇H₁₇ClN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 300.78

Ref: TM-T13691

Etifoxine

CAS: 21715-46-8

Purity: 98+%

Molecular weight: 300.79

Ref: 10-F979833

Etifoxine

Controlled Product

CAS: 21715-46-8

Formula: C₁₇H₁₇ClN₂O

Color and Shape: Neat

Molecular weight: 300.783

Ref: TR-E258070

Etifoxine

Controlled Product

CAS: 21715-46-8

Etifoxine is an anxiolytic drug that has been shown to inhibit axonal growth in vitro. It also has biological properties against infectious diseases such as HIV and tuberculosis, and has been shown to be effective in treatment trials for these diseases. Etifoxine inhibits the polymerase chain reaction (PCR) by binding to the DNA-dependent RNA polymerase enzyme, preventing transcription and replication of dsDNA. Etifoxine also binds to neurotransmitter receptors, including GABA-A, muscarinic M3, serotonin 5HT1A, and dopamine D2 receptors. This drug is often used in model systems for neurotrophic factors and experimental models for anxiety disorders.

Formula: C₁₇H₁₇ClN₂O

Purity: Min. 95%

Molecular weight: 300.78 g/mol

Ref: 3D-FE46731