CAS 21715-90-2

3a,4,7,7a-Tetrahydro-2-hydroxy-4,7-methano-1H-isoindole-1,3(2H)-dione

Description:

3a,4,7,7a-Tetrahydro-2-hydroxy-4,7-methano-1H-isoindole-1,3(2H)-dione, with the CAS number 21715-90-2, is a chemical compound that belongs to the class of isoindole derivatives. This substance features a bicyclic structure characterized by a fused isoindole ring system, which contributes to its unique chemical properties. The presence of a hydroxyl group (-OH) indicates potential for hydrogen bonding, influencing its solubility and reactivity. The compound is likely to exhibit moderate polarity due to the functional groups present. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, as isoindole derivatives are often explored for their biological activities. Additionally, the compound may participate in various chemical reactions, including nucleophilic substitutions and cycloadditions, making it of interest for synthetic organic chemistry. Overall, the characteristics of this compound highlight its significance in both theoretical studies and practical applications within the field of chemistry.

Formula: C₉H₉NO₃

InChI: InChI=1S/C9H9NO3/c11-8-6-4-1-2-5(3-4)7(6)9(12)10(8)13/h1-2,4-7,13H,3H2

InChI key: InChIKey=ZUSSTQCWRDLYJA-UHFFFAOYSA-N

SMILES: O=C1C2C(C3CC2C=C3)C(=O)N1O

Synonyms:

• (3aR,4S,7R,7aS)-2-hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
• (3aR,4S,7S,7aR)-2-hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
• 2-hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
• 3,5-Dioxo-4-azatricyclo[5.2.1.0²′⁶]dec-8-en-4-ol
• 3a,4,7,7a-Tetrahydro-2-hydroxy-4,7-methano-1H-isoindole-1,3(2H)-dione
• 4,7-Methano-1H-isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-hydroxy-
• 5-Norbornene-2,3-dicarboximide, N-hydroxy-
• Honb
• N-Hydroxy-5-bicyclo[2.2.1]heptene-2,3-dicarboximide
• N-Hydroxy-5-norbornene-endo-2,3-dicarboximide
• N-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-dicarboximide
• N-hydroxy-5-norbornene-2.3-dicarboxylimide
• NSC 100740
• NSC 12953
• endo-N-Hydroxy-5-norbornene-2,3-dicarboximide

N-Hydroxy-5-norbornene-2,3-dicarboximide [for Peptide Synthesis]

CAS: 21715-90-2

Formula: C₉H₉NO₃

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 179.18

Ref: 3B-H0528

endo-N-Hydroxy-5-norbornene-2,3-dicarboximide, 97%

CAS: 21715-90-2

It decreases racemization in peptide synthesis and inhibits formation of N-acylureas. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item

Formula: C₉H₉NO₃

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder or fused solid, White to pale cream

Molecular weight: 179.18

Ref: 02-A13205

2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione

CAS: 21715-90-2

Formula: C₉H₉NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 179.1727

Ref: IN-DA003T2G

endo-N-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-dicarboximide

CAS: 21715-90-2

endo-N-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-dicarboximide

Purity: 98%

Color and Shape: Beige Solid

Molecular weight: 179.17g/mol

Ref: 54-OR14538

N-Hydroxy-5-norbornene-2,3-dicarboximide (HONB)

CAS: 21715-90-2

Formula: C₉H₉NO₃

Molecular weight: 179.18

Ref: 7W-GE8919

N-Hydroxy-5-norbornene-2,3-dicarboximide

CAS: 21715-90-2

Formula: C₉H₉NO₃

Purity: 95.0%

Color and Shape: Solid, Powder or Crystalline Powder or Solid or Chunks

Molecular weight: 179.058

Ref: 10-F022118

HONB

Controlled Product

CAS: 21715-90-2

Applications HONB is used in solution-phase peptide synthesis. Used in the synthesis of enkephalin analogs.
References Mahindra, A. et al.: Tetrahedron Lett., 53, 6391 (2012); Irina, B. et al.: Eur. J. Med. Chem., 33, 255 (1998);

Formula: C₉H₉NO₃

Color and Shape: Neat

Molecular weight: 179.17

Ref: TR-H669550