CAS 21736-83-4

Spectinomycin hydrochloride

Description:

Spectinomycin hydrochloride is an antibiotic that belongs to the aminocyclitol class and is primarily used to treat bacterial infections, particularly those caused by Neisseria gonorrhoeae. It functions by inhibiting protein synthesis in bacteria, effectively halting their growth. The compound is a white to off-white crystalline powder that is soluble in water, making it suitable for parenteral administration. Its chemical structure features a cyclohexane ring and multiple hydroxyl groups, contributing to its biological activity. Spectinomycin is often administered via injection and is particularly noted for its effectiveness in treating gonorrhea, especially in cases where other antibiotics may not be effective due to resistance. The hydrochloride form enhances its stability and solubility. While generally well-tolerated, potential side effects can include gastrointestinal disturbances and allergic reactions. As with any antibiotic, appropriate use is crucial to minimize the development of resistance. Spectinomycin is included in various treatment guidelines for sexually transmitted infections, reflecting its importance in clinical practice.

Formula: C₁₄H₂₄N₂O₇·2ClH

InChI: InChI=1S/C14H24N2O7.2ClH/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;/m1../s1

InChI key: InChIKey=FOGDPGQSHLLYIK-XYQGXRRISA-N

SMILES: N(C)[C@@H]1[C@@]2([C@](O[C@]3([C@@](O)(O2)C(=O)C[C@@H](C)O3)[H])([C@@H](O)[C@H](NC)[C@@H]1O)[H])[H].Cl

Synonyms:

• 4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-
• 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, dihydrochloride, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-
• 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, dihydrochloride, [2R-(2α,4aβ,5aβ,6β,7β,8β,9α,9aα,10aβ)]-
• 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, hydrochloride (1:2), (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-
• 4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one
• NSC 248616
• Spectinomycin HCl
• Spectinomycin dihydrochloride
• Stanilo
• Spectinomycin hydrochloride

Spectinomycin Dihydrochloride Pentahydrate

CAS: 1695-77-8, 21736-83-4, 22189-32-8

Formula: C₁₄H₂₄N₂O₇·2HCl·5H₂O

Purity: >98.0%(T)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 495.35

Ref: 3B-S0584

Spectinomycin dihydrochloride

CAS: 21736-83-4

Spectinomycin dihydrochloride, an antibiotic from Streptomyces spectabilis, treats gonorrhea and targets gram-negative bacteria.

Formula: C₁₄H₂₆Cl₂N₂O₇

Purity: 99.67% - >99.99%

Color and Shape: Powder

Molecular weight: 405.271

Ref: TM-T0788

4H-PYRANO[2,3-B][1,4]BENZODIOXIN-4-ONE,DECAHYDRO-4A,7,9-TRIHYDROXY-2-METHYL-6,8-BIS(METHYLAMINO)-,DIHYDROCHLORIDE, (2R,4AR,5AR,6S,7S,8R,9S,9AR,10AS)-

CAS: 21736-83-4

Formula: C₁₄H₂₆Cl₂N₂O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 405.2714

Ref: IN-DA00I47Z

Spectinomycin dihydrochloride

CAS: 21736-83-4

Spectinomycin dihydrochloride

Purity: ≥98%

Molecular weight: 405.271g/mol

Ref: 54-BUP18847

Spectinomycin Dihydrochloride

CAS: 21736-83-4

Applications An antibiotic used in the treatment and control of infectious bacterial enteritis in animals. Used in drug testing against nonreplicating mycobacterium tuberculosis.
References Sala, C. et al.: Antimicrob. Agents Chemother., 54, 4150 (2010); Food and Drug Admin.: Fed. Reg., 69, 52815 (2004);

Formula: C₁₄H₂₄N₂O₇·2ClH

Color and Shape: White To Off-White

Molecular weight: 405.2714

Ref: TR-S680250