CAS 21739-92-4

5-Bromo-2-chlorobenzoic acid

Description:

5-Bromo-2-chlorobenzoic acid is an aromatic carboxylic acid characterized by the presence of both bromine and chlorine substituents on the benzene ring. Specifically, it features a bromine atom at the 5-position and a chlorine atom at the 2-position relative to the carboxylic acid group. This compound typically appears as a white to off-white solid and is sparingly soluble in water, but more soluble in organic solvents such as ethanol and acetone. It exhibits moderate acidity due to the carboxylic acid functional group, which can participate in hydrogen bonding. The presence of halogen substituents can influence its reactivity, making it useful in various chemical syntheses, including the preparation of pharmaceuticals and agrochemicals. Additionally, 5-Bromo-2-chlorobenzoic acid can serve as an intermediate in organic synthesis, particularly in reactions involving electrophilic aromatic substitution. Safety precautions should be taken when handling this compound, as it may pose health risks if ingested or inhaled, and appropriate protective equipment should be used.

Formula: C₇H₄BrClO₂

InChI: InChI=1S/C7H4BrClO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,(H,10,11)

InChI key: InChIKey=FGERXQWKKIVFQG-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(Cl)C=CC(Br)=C1

Synonyms:

• 2-Chloro-5-bromobenzoic acid
• 2-Chloropyridine-4-Carbonitrile
• 5-Bromo-2-Chlorobenzoate
• 5-Bromo-2-chloro-benzoic acid
• Bcba
• Benzoic acid, 5-bromo-2-chloro-
• 5-Bromo-2-chlorobenzoic acid

5-Bromo-2-chlorobenzoic Acid

CAS: 21739-92-4

Formula: C₇H₄BrClO₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 235.46

Ref: 3B-B1344

5-Bromo-2-chlorobenzoic acid, 98+%

CAS: 21739-92-4

5-Bromo-2-chlorobenzoic acid was used to evaluate the homogeneity of organic powder. It can be used to produce 2-chloro-5-deuteriobenzoic acid. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer

Formula: C₇H₃BrClO₂

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 234.45

Ref: 02-A12218

5-Bromo-2-Chlorobenzoic Acid

CAS: 21739-92-4

Formula: C₇H₄BrClO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.4625

Ref: IN-DA00347J

Dapagliflozin Impurity 19

CAS: 21739-92-4

Formula: C₇H₄BrClO₂

Molecular weight: 235.46

Ref: 4Z-D-6225

5-Bromo-2-chlorobenzoic acid

CAS: 21739-92-4

5-Bromo-2-chlorobenzoic acid

Formula: C₇H₄BrClO₂

Purity: 98%

Color and Shape: white to off white solid

Molecular weight: 235.46g/mol

Ref: 54-OR1038

5-Bromo-2-Chlorobenzoic Acid

CAS: 21739-92-4

Formula: C₇H₄BrClO₂

Molecular weight: 235.46

Ref: ST-EA-CP-D8038

5-Bromo-2-chlorobenzoic acid

CAS: 21739-92-4

Formula: C₇H₄BrClO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.46

Ref: 10-F075288

5-Bromo-2-chlorobenzoic Acid

Controlled Product

CAS: 21739-92-4

Applications 5-Bromo-2-chlorobenzoic acid is used as a starting material in the synthesis of Dapagliflozin (D185370), a selective sodium-glucose cotransporter-2 inhibitor that reduces renal glucose reabsorption and is used to treat patients with type 2 diabetes.
References List, J., et al.: Diabetes Care, 32, 650 (2009); Meng, W., et al.: J. Med. Chem., 51, 1145 (2008); Wilding, J., et al.: Diabetes Care, 32, 1656 (2009)

Formula: C₇H₄BrClO₂

Color and Shape: Neat

Molecular weight: 235.46

Ref: TR-B682120

5-Bromo-2-chlorobenzoic acid

CAS: 21739-92-4

Intermediate in the synthesis of dapagliflozin

Formula: C₇H₄BrClO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 235.46 g/mol

Ref: 3D-FB64184