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CAS 2174002-16-3

:

Palbociclib-025

Description:
Palbociclib-025, identified by its CAS number 2174002-16-3, is a chemical compound primarily recognized for its role as a selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK4 and CDK6. This inhibition is crucial in regulating the cell cycle, making it a significant compound in cancer research, especially for the treatment of hormone receptor-positive breast cancer. The compound is characterized by its ability to interfere with the phosphorylation of retinoblastoma protein, thereby halting cell proliferation. Palbociclib-025 is typically studied in the context of its pharmacological properties, including its efficacy, bioavailability, and safety profile. It is often administered in conjunction with other therapeutic agents to enhance its anticancer effects. The compound's molecular structure includes specific functional groups that contribute to its biological activity, and its synthesis involves complex organic reactions. As with many pharmaceuticals, ongoing research aims to better understand its mechanisms of action, potential side effects, and optimal therapeutic regimens.
Formula:C25H29N7O3
Synonyms:
  • Palbociclib E
  • Palbociclib Impurity 025
  • 1-Piperazinecarboxaldehyde, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-
  • 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde? (Palbociclib Impurity）
  • N-Formyl Palbociclib
  • Palbociclib impurity 27/Palbociclib N-Formyl Impurity/4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde
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