CAS 217461-40-0

2H-Benzimidazol-2-one,1-[(3R,4R)-1-(cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-, rel-

Description:

2H-Benzimidazol-2-one, 1-[(3R,4R)-1-(cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-, rel- (CAS 217461-40-0) is a chemical compound characterized by its complex structure, which includes a benzimidazole core fused with a piperidine ring. This compound exhibits a range of pharmacological properties, often studied for its potential therapeutic applications. The presence of the cyclooctylmethyl group and hydroxymethyl substituent contributes to its unique steric and electronic properties, influencing its interaction with biological targets. The stereochemistry indicated by the (3R,4R) configuration suggests specific spatial arrangements that may enhance its binding affinity and selectivity. Additionally, the ethyl group at the benzimidazole position may affect solubility and permeability. Overall, this compound represents a class of molecules that may be of interest in medicinal chemistry, particularly in the development of new drugs targeting various biological pathways.

Formula: C₂₄H₃₇N₃O₂

(±)-J 113397

CAS: 217461-40-0

(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).

Formula: C₂₄H₃₇N₃O₂

Color and Shape: Solid

Molecular weight: 399.57

Ref: TM-T21999