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CAS 217959-45-0

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5-(trifluoromethyl)thiophen-3-ol

Description:
5-(Trifluoromethyl)thiophen-3-ol is an organic compound characterized by the presence of a thiophene ring, which is a five-membered aromatic heterocycle containing sulfur. The compound features a trifluoromethyl group (-CF3) attached to the fifth position of the thiophene ring and a hydroxyl group (-OH) at the third position. This unique substitution pattern imparts distinct chemical properties, including increased lipophilicity and potential reactivity due to the electronegative trifluoromethyl group. The presence of the hydroxyl group suggests that the compound can participate in hydrogen bonding, influencing its solubility and reactivity in various solvents. Additionally, the trifluoromethyl group is known to enhance the compound's stability and can affect its biological activity, making it of interest in medicinal chemistry and materials science. Overall, 5-(trifluoromethyl)thiophen-3-ol exhibits characteristics typical of both thiophene derivatives and fluorinated compounds, contributing to its potential applications in various chemical contexts.
Formula:C5H3F3OS
Synonyms:
  • Thiophene-3-ol, 5-(trifluoromethyl)-
  • 3-Hydroxy-5-trifluoromethylthiophene
  • 5-Trifluoromethyl-3-hydroxythiophene
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