CAS 217973-03-0

DO3A

Description:

DO3A, or 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid, is a polyaminocarboxylic acid that serves as a chelating agent, particularly for metal ions. It features a cyclic structure with four nitrogen atoms and three carboxylic acid groups, which allows it to effectively bind to various metal ions, making it useful in applications such as radiopharmaceuticals and metal ion separation. The compound is characterized by its high stability and selectivity for certain metal ions, including lanthanides and actinides, which is advantageous in nuclear medicine and imaging. DO3A is typically synthesized through multi-step organic reactions and is soluble in water, enhancing its utility in biological systems. Its ability to form stable complexes with metals is attributed to the chelation effect, which significantly reduces the toxicity of the metal ions while facilitating their transport in biological environments. Overall, DO3A is an important compound in both analytical chemistry and medical applications, particularly in the development of targeted therapies and diagnostic agents.

Synonyms:

• 1,4,7,10-Tetraazacyclododecaan-1,4,7-Triyltriazijnzuur

DO3A

CAS: 217973-03-0

Formula: C₁₄H₂₃N₄Na₃O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 412.3249

Ref: IN-DA00BJQG

Sodium 2,2',2''-(1,4,7,10-Tetraazacyclododecane-1,4,7-Triyl)Triacetate

CAS: 217973-03-0

Sodium 2,2',2''-(1,4,7,10-Tetraazacyclododecane-1,4,7-Triyl)Triacetate

Purity: 97%

Molecular weight: 412.32g/mol

Ref: 54-OR1024699

DO3A

Controlled Product

CAS: 217973-03-0

Applications DO3A is a macrocyclic chelating agent that can be used as a luminescent sensor to detect NAD(P)H based on Ln(III) ternary complexes.
References Smrcka, F., et.al., Molecules, 25, 4164, (2020); Zhou, X., et.al., Faming Zhuanli Shenqing, 14, (2020);

Formula: C₁₄H₂₃N₄O₆•3(Na)

Color and Shape: Neat

Molecular weight: 366.15153

Ref: TR-D494885