N3-PEG8-CH2CO2-NHS is a chemical compound that features a combination of a polyethylene glycol (PEG) moiety and a N-hydroxysuccinimide (NHS) ester, which is commonly used in bioconjugation and drug delivery applications. The "N3" indicates the presence of an azide functional group, which can participate in click chemistry reactions, making it useful for labeling and attaching biomolecules. The PEG segment provides hydrophilicity, enhancing solubility in aqueous environments and improving the pharmacokinetic properties of conjugated drugs. The carboxylic acid group (CH2CO2) allows for further functionalization or conjugation with amine-containing molecules. The NHS group is particularly valuable for forming stable amide bonds with primary amines, facilitating the attachment of proteins, peptides, or other biomolecules. Overall, N3-PEG8-CH2CO2-NHS is characterized by its versatility in bioconjugation, solubility, and ability to facilitate targeted delivery in various biomedical applications.

Azido-PEG8-CH2CO2-NHS is a monodisperse, high purity PEG linker containing an azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. Azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistrye. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

N3-PEG8-CH2CO2-NHS

2182601-81-4: N3-PEG8-CH2CO2-NHS is a chemical compound that features a combination of a polyethylene glycol (PEG) moiety and a N-hydroxysuccinimide (NHS) ester, which is commonly used in bioconjugation and drug delivery applications. The "N3" indicates the presence of an azide functional group, which can participate in click chemistry reactions, making it useful for labeling and attaching biomolecules. The PEG segment provides hydrophilicity, enhancing solubility in aqueous environments and improving the pharmacokinetic properties of conjugated drugs. The carboxylic acid group (CH2CO2) allows for further functionalization or conjugation with amine-containing molecules. The NHS group is particularly valuable for forming stable amide bonds with primary amines, facilitating the attachment of proteins, peptides, or other biomolecules. Overall, N3-PEG8-CH2CO2-NHS is characterized by its versatility in bioconjugation, solubility, and ability to facilitate targeted delivery in various biomedical applications.

Azido-PEG8-C1-NHS ester is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

CAS 2182601-81-4

N3-PEG8-CH2CO2-NHS

Azido-PEG8-C1-NHS ester

Ref: TM-T14477