CAS 2183470-09-7

GCN2-IN-6

CAS: 2183470-09-7

GCN2-IN-6

Purity: ≥95%

Molecular weight: 485.29g/mol

Ref: 54-BUP14401

GCN2-IN-6

CAS: 2183470-09-7

GCN2-IN-6 is a potent and selective activator of the GCN2 protein kinase. GCN2 is a serine/threonine protein kinase that phosphorylates eIF2α, leading to an increase in protein synthesis. The GCN2-IN-6 peptide can be used as a research tool to investigate the role of GCN2 in cell biology and for the study of ion channels, peptides and antibodies.
GCN2-IN-6 has been shown to inhibit antibody production by inhibiting protein interactions with B cells and macrophages, which are important for antibody production.

Formula: C₁₉H₁₂Cl₂F₂N₄O₃S

Purity: Min. 95%

Molecular weight: 485.3 g/mol

Ref: 3D-IMD47009

GCN2-IN-6

CAS: 2183470-09-7

GCN2-IN-6: Potent, oral GCN2/PERK inhibitor; IC50s - GCN2: 1.8 nM (enzymatic), 9.3 nM (cellular); PERK: 0.26 nM (enzymatic), 230 nM (cellular).

Formula: C₁₉H₁₂Cl₂F₂N₄O₃S

Purity: 95.04% - 98%

Color and Shape: Solid

Molecular weight: 485.29

Ref: TM-T11374