Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin, a type of protein that plays a crucial role in the development, maintenance, and survival of neurons in the human brain. It is essential for neurogenesis, synaptic plasticity, and overall brain health. BDNF is involved in various physiological processes, including learning, memory, and mood regulation. The human form of BDNF is encoded by the BDNF gene and is synthesized as a precursor protein that undergoes proteolytic cleavage to become biologically active. The CAS number 218441-99-7 specifically identifies this protein, which is often studied in the context of neurodegenerative diseases, psychiatric disorders, and brain injuries. BDNF exerts its effects by binding to specific receptors, primarily the TrkB receptor, triggering signaling pathways that promote neuronal survival and growth. Its levels can be influenced by various factors, including physical activity, stress, and certain medications, making it a significant focus of research in neuroscience and therapeutic interventions.

Brain Derived Neurotrophic Factor, Human

218441-99-7: Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin, a type of protein that plays a crucial role in the development, maintenance, and survival of neurons in the human brain. It is essential for neurogenesis, synaptic plasticity, and overall brain health. BDNF is involved in various physiological processes, including learning, memory, and mood regulation. The human form of BDNF is encoded by the BDNF gene and is synthesized as a precursor protein that undergoes proteolytic cleavage to become biologically active. The CAS number 218441-99-7 specifically identifies this protein, which is often studied in the context of neurodegenerative diseases, psychiatric disorders, and brain injuries. BDNF exerts its effects by binding to specific receptors, primarily the TrkB receptor, triggering signaling pathways that promote neuronal survival and growth. Its levels can be influenced by various factors, including physical activity, stress, and certain medications, making it a significant focus of research in neuroscience and therapeutic interventions.

<p>BDNF, a neurotrophin, activates TrkB/p75 receptors, aids neuron survival and growth, and is linked to Parkinson's and Alzheimer's.</p>

CAS 218441-99-7

Brain Derived Neurotrophic Factor, Human

BDNF (human)

Ref: TM-TP2069

rHuBDNF

Ref: 54-BITP1018