CAS 2185859-59-8

6-(Difluoromethyl)-8-[(1S,2S)-2-hydroxy-2-methylcyclopentyl]-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one

Description:

The chemical substance known as 6-(Difluoromethyl)-8-[(1S,2S)-2-hydroxy-2-methylcyclopentyl]-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one, with the CAS number 2185859-59-8, is a complex organic compound characterized by its unique structural features. It contains a pyrido[2,3-d]pyrimidinone core, which is a bicyclic structure that contributes to its biological activity. The presence of a difluoromethyl group and a methylsulfonyl moiety indicates potential for interactions with biological targets, possibly enhancing its pharmacological properties. The compound also features a cyclopentyl ring with a hydroxyl group, suggesting it may exhibit specific stereochemical properties that could influence its binding affinity and selectivity. Overall, this substance is likely to be of interest in medicinal chemistry, particularly in the development of therapeutics, due to its intricate structure and potential biological implications. Further studies would be necessary to elucidate its specific properties, mechanisms of action, and potential applications in drug development.

Formula: C₂₀H₂₇F₂N₅O₄S

InChI: InChI=1S/C20H27F2N5O4S/c1-20(29)7-3-4-15(20)27-17-12(10-14(16(21)22)18(27)28)11-23-19(25-17)24-13-5-8-26(9-6-13)32(2,30)31/h10-11,13,15-16,29H,3-9H2,1-2H3,(H,23,24,25)/t15-,20-/m0/s1

InChI key: InChIKey=QIEKHLDZKRQLLN-YWZLYKJASA-N

SMILES: O=C1N(C=2C(C=C1C(F)F)=CN=C(NC3CCN(S(C)(=O)=O)CC3)N2)[C@@H]4[C@@](C)(O)CCC4

Synonyms:

• 6-(Difluoromethyl)-8-[(1S,2S)-2-hydroxy-2-methylcyclopentyl]-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
• Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(difluoromethyl)-8-[(1S,2S)-2-hydroxy-2-methylcyclopentyl]-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-

(S)-PF-06873600

CAS: 2185859-59-8

(S)-PF-06873600

Purity: ≥98%

Molecular weight: 471.52g/mol

Ref: 54-BUP01422

(S)-PF-06873600

CAS: 2185859-59-8

(S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK.

Formula: C₂₀H₂₇F₂N₅O₄S

Purity: 98.59%

Color and Shape: Solid

Molecular weight: 471.52

Ref: TM-T12809