As of my last update in October 2023, there is limited publicly available information regarding the chemical substance known as DI-404 with the CAS number 2187412-79-7. This compound may be a specialized or proprietary chemical, potentially used in specific industrial applications, research, or development contexts. Typically, substances like this may exhibit unique properties such as specific solubility, reactivity, or stability under certain conditions, which are crucial for their intended use. However, without detailed data or a safety data sheet (SDS), it is challenging to provide precise characteristics such as molecular structure, physical properties, or safety information. For accurate and comprehensive details, consulting scientific literature, product specifications, or databases that specialize in chemical substances would be necessary. Always ensure to handle any chemical with appropriate safety measures and guidelines.

DI-404 is a high-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction (Kd= 6.9 nM). DI-404 effectively and selectively inhibits the neddylation of cullin 3 over other cullin members. Further optimization of DI-404 may yield a new class of therapeutics for the treatment of human diseases in which cullin 3 CRL plays a key role.

DI-404

2187412-79-7: As of my last update in October 2023, there is limited publicly available information regarding the chemical substance known as DI-404 with the CAS number 2187412-79-7. This compound may be a specialized or proprietary chemical, potentially used in specific industrial applications, research, or development contexts. Typically, substances like this may exhibit unique properties such as specific solubility, reactivity, or stability under certain conditions, which are crucial for their intended use. However, without detailed data or a safety data sheet (SDS), it is challenging to provide precise characteristics such as molecular structure, physical properties, or safety information. For accurate and comprehensive details, consulting scientific literature, product specifications, or databases that specialize in chemical substances would be necessary. Always ensure to handle any chemical with appropriate safety measures and guidelines.

DI-404: Potent DCN1-UBC12 inhibitor, selectivity blocks cullin 3 neddylation, Kd=6.9 nM.

CAS 2187412-79-7

DI-404

DI-404

Ref: TM-T23989