CAS 2188-18-3

N2-[(1,1-Dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-L-ornithine

Description:

N2-[(1,1-Dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-L-ornithine, with the CAS number 2188-18-3, is a synthetic compound that belongs to the class of amino acids and derivatives. This substance features a complex structure characterized by the presence of an ornithine backbone, which is an important amino acid involved in the urea cycle. The molecule is modified with a dimethylethoxycarbonyl group, enhancing its stability and solubility. Additionally, the presence of an imino group and nitroamino functionality suggests potential reactivity and biological activity, possibly influencing its role in biochemical pathways. The compound may exhibit properties such as being a potential intermediate in the synthesis of pharmaceuticals or agrochemicals. Its unique structure may also confer specific interactions with biological targets, making it of interest in medicinal chemistry. However, detailed studies on its biological activity, toxicity, and environmental impact would be necessary to fully understand its characteristics and applications.

Formula: C₁₁H₂₁N₅O₆

InChI: InChI=1S/C11H21N5O6/c1-11(2,3)22-10(19)14-7(8(17)18)5-4-6-13-9(12)15-16(20)21/h7H,4-6H2,1-3H3,(H,14,19)(H,17,18)(H3,12,13,15)/t7-/m0/s1

InChI key: InChIKey=OZSSOVRIEPAIMP-ZETCQYMHSA-N

SMILES: [C@H](NC(OC(C)(C)C)=O)(CCCNC(NN(=O)=O)=N)C(O)=O

Synonyms:

• (2S)-2-(tert-Butoxycarbonylamino)-5-[(N-nitrocarbamimidoyl)amino]pentanoic acid
• (2S)-2-[[(tert-Butoxy)carbonyl]amino]-5-(N′-nitrocarbamimidamido)pentanoic acid
• (2S)-5-[Amino(nitramido)methylidene]azaniumyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate
• <span class="text-smallcaps">L</span>-Ornithine, N²-[(1,1-dimethylethoxy)carbonyl]-N⁵-[imino(nitroamino)methyl]-
• Boc-Arg(NO2)-OH
• Boc-Arg(No2)
• Boc-L-nitroarginine
• N-Boc-N'-nitro-L-arginine
• N²-[(1,1-Dimethylethoxy)carbonyl]-N⁵-[imino(nitroamino)methyl]-<span class="text-smallcaps">L</span>-ornithine
• N²-tert-Butoxycarbonyl-N^G-nitroarginine
• N²-tert-Butyloxycarbonyl-N^ω-nitro-<span class="text-smallcaps">L</span>-arginine
• N^α-tert-Butoxycarbonyl-N^G-nitro-<span class="text-smallcaps">L</span>-arginine
• N^α-tert-Butoxycarbonyl-N^G-nitroarginine
• Ornithine, N²-carboxy-N⁵-(nitroamidino)-, N-tert-butyl ester
• Ornithine, N²-carboxy-N⁵-(nitroamidino)-, N²-tert-butyl ester, <span class="text-smallcaps">L</span>-
• Nα-tert-Butoxycarbonyl-NG-nitro-L-arginine
• Ornithine, N2-carboxy-N5-(nitroamidino)-, N-tert-butyl ester
• N2-[(1,1-Dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-L-ornithine
• L-Ornithine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-

Nα-Boc-N^w-nitro-L-arginine, 98%

CAS: 2188-18-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₁H₂₁N₅O₆

Purity: 98%

Molecular weight: 319.32

Ref: 02-H62339

Boc-Arg(NO₂)-OH

CAS: 2188-18-3

The nitro group of the guanidyl residue can be removed by treating the blocked peptide with HF at 0 °C for 40 min.

Formula: C₁₁H₂₁N₅O₆

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 319.32

Ref: 01-4001219

N-Boc-N'-Nitro-L-arginine

CAS: 2188-18-3

Formula: C₁₁H₂₁N₅O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 319.3143

Ref: IN-DA0038VM

N-α-BOC-N-ω-Nitro-L-arginine

CAS: 2188-18-3

N-α-BOC-N-ω-Nitro-L-arginine

Formula: C₁₁H₂₁N₅O₆

Purity: 98%

Color and Shape: off-white solid

Molecular weight: 319.31g/mol

Ref: 54-OR0122

Boc-Arg(NO2)-OH

CAS: 2188-18-3

Molecular weight: 319.31

Ref: 7W-GM5650

Boc-Arg(NO2)-OH

CAS: 2188-18-3

Formula: C₁₁H₂₁N₅O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 319.32

Ref: 3B-B4496

Boc-L-Arg(NO2)-OH

CAS: 2188-18-3

Formula: C₁₁H₂₁N₅O₆

Molecular weight: 319.32

Ref: 4Z-A-9232

Boc-L-Nitroarginine

Controlled Product

CAS: 2188-18-3

Applications Boc-L-Nitroarginine, can be used in peptide chemistry. It has been also shown to act as NO synthase inhibitor, and thus used in the study of The effects of methylene blue (MB) for treatment of sepsis induced by bowel perforation.
References Galili, Y. Euro. surg. Rese. vol. 29, P:390-395 (19997);

Formula: C₁₁H₂₁N₅O₆

Color and Shape: Neat

Molecular weight: 319.31

Ref: TR-B391615

Boc-Arg(NO2)-OH

CAS: 2188-18-3

Boc-Arg(NO2)-OH is an activated molecule that is used as an anticoagulant. It inhibits the serine protease, which has an inhibitory effect on heparin-induced thrombocytopenia, and also inhibits platelet aggregation. Boc-Arg(NO2)-OH has been shown to have a potent inhibition of the enzyme that converts prothrombin into thrombin. This effect can be reversed by adding protamine sulfate. The clinical data suggest that this drug may be beneficial for patients with severe or life-threatening conditions who are taking heparin therapy or undergoing surgery and need anticoagulation. The prognosis of this drug is unclear, but it appears to be safe when administered in conjunction with other medications such as aspirin and warfarin.

Formula: C₁₀H₁₉NO₄

Purity: Min. 95%

Molecular weight: 319.32 g/mol

Ref: 3D-BLR-2058

BOC-Nitro-L-Arginine extrapure, 99%

CAS: 2188-18-3

Formula: C₁₁H₂₁N₅O₆

Purity: min. 99%

Color and Shape: White, Powder

Molecular weight: 319.31

Ref: SR-53717

Boc-Arg(NO2)-OH

CAS: 2188-18-3

M03259 - Boc-Arg(NO2)-OH

Formula: C₁₁H₂₁N₅O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 319.318

Ref: 10-M03259

Boc-L-Nitroarginine

CAS: 2188-18-3

Formula: C₁₁H₂₁N₅O₆

Molecular weight: 319.32

Ref: ST-EA-CP-A123015

Boc-L-Nitroarginine

CAS: 2188-18-3

Boc-L-Nitroarginine is a nitric oxide synthase inhibitor that belongs to the class of drugs called nitric oxide inhibitors. It is a potent inhibitor of nitric oxide synthase, preventing the production of nitric oxide from arginine. The drug has been shown to have therapeutic effects in the treatment of cancer, diabetes mellitus, and other diseases. Boc-L-Nitroarginine inhibits tumor angiogenesis by blocking endothelial cell proliferation and migration. It also inhibits insulin secretion, leading to an improved glycemic control in diabetic patients. Boc-L-Nitroarginine can be used as a hydrogenation reducing agent for the synthesis of imatinib and palladium catalysts for hydrogenation reactions.

Formula: C₁₁H₂₁N₅O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 319.31 g/mol

Ref: 3D-FB39246