CAS 2188-68-3

Lycorine hydrochloride

Description:

Lycorine hydrochloride is a naturally occurring alkaloid derived from various species of the Amaryllidaceae family, particularly from the plant Lycoris. It is characterized by its white to off-white crystalline appearance and is soluble in water and alcohol. Lycorine exhibits a range of biological activities, including antiviral, anticancer, and anti-inflammatory properties, making it a subject of interest in pharmacological research. The compound acts as an inhibitor of protein synthesis and has been shown to interfere with various cellular processes. Its mechanism of action involves the inhibition of certain enzymes and pathways, which can lead to apoptosis in cancer cells. Additionally, lycorine has been studied for its potential effects on neurodegenerative diseases and as an antimicrobial agent. However, its use is limited due to potential toxicity and side effects, necessitating careful consideration in therapeutic applications. As with any bioactive compound, further research is essential to fully understand its pharmacokinetics, safety profile, and potential therapeutic uses.

Formula: C₁₆H₁₇NO₄

InChI: InChI=1/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1

InChI key: InChIKey=VUVNTYCHKZBOMV-NVJKKXITSA-N

SMILES: O[C@H]1[C@@]2([C@@]3(N(CC=4C2=CC5=C(C4)OCO5)CCC3=C[C@@H]1O)[H])[H].Cl

Synonyms:

• (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol hydrochloride (1:1)
• 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, hydrochloride (1:1), (1S,2S,12bS,12cS)-
• 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, hydrochloride, (1S,2S,12bS,12cS)-
• Galanthan-1,2-diol, 3,12-didehydro-9,10-[methylenebis(oxy)]-, hydrochloride, (1α,2β)-
• Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)-
• Galanthidine hydrochloride
• Licorin hydrochloride
• Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-, hydrochloride
• Lycoran-1α,2β-diol, 3,3a-didehydro-, hydrochloride
• Lycorine HCl
• Lycorine hydrochloride
• (1S,2S,12BS,12CS)-1,2,4,5,12B,12C-HEXAHYDRO-7H-[1,3]DIOXOLO[4,5-J]PYRROLO[3,2,1-DE]PHENANTHRIDINE-1,2-DIOL
• LYCORIN
• Lycorine hydrochloride USP/EP/BP
• Lycorine hydrochloride, 96%(HPLC)
• NARCISSIN(P)
• Narcissine hydrochloride
• Lycorinehydrochloride 2188-68-3
• LYCORINE
• Lycorine chloride
• Amarylline hydrochloride
• Lycorine Hydrochloride98%
• Lycorine chloride 2188-68-3
• (-)-LYCORINE
• Licorine hydrochloride

1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride (1:1), (1S,2S,12bS,12cS)-

CAS: 2188-68-3

Formula: C₁₆H₁₈ClNO₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 323.7714

Ref: IN-DA006YZ0

Lycorine hydrochloride

CAS: 2188-68-3

Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.

Formula: C₁₆H₁₈ClNO₄

Purity: 99.45% - 99.49%

Color and Shape: Fine Crystal Powder

Molecular weight: 323.77

Ref: TM-T2774

Lycorine hydrochloride

CAS: 2188-68-3

Lycorine hydrochloride

Purity: ≥98%

Molecular weight: 323.77g/mol

Ref: 54-BUP11762

Lycorine hydrochloride

CAS: 2188-68-3

Formula: C₁₆H₁₇NO₄·HCl

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 323.77

Ref: 7W-GK0766

Lycorine hydrochloride

CAS: 2188-68-3

Lycorine hydrochloride

Purity: 98%

Molecular weight: 323.77g/mol

Ref: 54-OR1027210

Lycorine hydrochloride

CAS: 2188-68-3

Formula: C₁₆H₁₈ClNO₄

Purity: 95%~99%

Molecular weight: 323.773

Ref: BP-BP0905

Lycorine Hydrochloride Monohydrate

CAS: 2188-68-3, 6150-58-9

Formula: C₁₆H₁₇NO₄·HCl·H₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 341.79

Ref: 3B-L0319

Lycorine HCl

CAS: 2188-68-3

Formula: C₁₆H₁₇NO₄·HCl

Molecular weight: 287.32 36.46

Ref: 4Z-L-139001

Lycorine hydrochloride

CAS: 2188-68-3

Natural alkaloid

Formula: C₁₆H₁₇NO₄HCl

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 323.77

Ref: 5G-82582

Lycorine Hydrochloride

Controlled Product

CAS: 2188-68-3

Stability Hygroscopic
Applications Lycorine Hydrochloride is the main phenanthridine Amaryllidaceae alkaloid which exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli.
References Lamoral-Theys. D., et al.: J. Med. Chem., 52, 6244 (2009); Cao, Z.F., et al.: Toxicol. Lett., 218, 174 (2013); Brunhofer, G., et al.: Bioorg. med. Chem., 20, 6669 (2012);

Formula: C₁₆H₁₇NO₄·ClH

Color and Shape: Neat

Molecular weight: 323.7714

Ref: TR-L487550

Lycorine HCl

CAS: 2188-68-3

Lycorine HCl is an alkaloid derivative, which is a chemical compound extracted from plants of the Amaryllidaceae family. Lycorine is known for its complex structure and its source from plants such as the Lycoris radiata, commonly referred to as red spider lily. The hydrochloride salt form of this alkaloid is studied for its increased solubility and stability, making it easier to handle in laboratory settings.

Formula: C₁₆H₁₇NO₄HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 323.77 g/mol

Ref: 3D-FL65308

Lycorine Hydrochloride

CAS: 2188-68-3

Formula: C₁₆H₁₈ClNO₄

Purity: 99%

Molecular weight: 323.77

Ref: 10-F547228