CAS 21881-78-7

3,5-Bis(1-methylethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

Description:

3,5-Bis(1-methylethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, with CAS number 21881-78-7, is a chemical compound that belongs to the class of pyridine derivatives. This substance features a pyridine ring substituted with multiple functional groups, including two ester groups and a nitrophenyl moiety, which contribute to its chemical reactivity and potential applications. The presence of the isopropyl groups enhances its lipophilicity, potentially affecting its solubility in organic solvents. The nitro group introduces electron-withdrawing characteristics, which can influence the compound's reactivity and interaction with biological systems. This compound may exhibit interesting pharmacological properties, making it a candidate for further research in medicinal chemistry. Its structural complexity suggests potential utility in various chemical syntheses or as a building block in the development of more complex molecules. However, specific safety and handling information should be consulted, as with any chemical substance, to ensure proper laboratory practices.

Formula: C₂₁H₂₆N₂O₆

InChI: InChI=1S/C21H26N2O6/c1-11(2)28-20(24)17-13(5)22-14(6)18(21(25)29-12(3)4)19(17)15-8-7-9-16(10-15)23(26)27/h7-12,19,22H,1-6H3

InChI key: InChIKey=UPOXKUKUWZYRQV-UHFFFAOYSA-N

SMILES: C(OC(C)C)(=O)C=1C(C(C(OC(C)C)=O)=C(C)NC1C)C2=CC(N(=O)=O)=CC=C2

Synonyms:

• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, bis(1-methylethyl) ester
• 3,5-Bis(1-methylethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-, diisopropyl ester
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3,5-bis(1-methylethyl) ester
• 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diisopropyl ester

Diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (Nimodipine Impurity)

CAS: 21881-78-7

Diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (Nimodipine Impurity)

Purity: 98%

Ref: 54-OR1042212

Nimodipine EP Impurity B

CAS: 21881-78-7

Formula: C₂₁H₂₆N₂O₆

Color and Shape: Pale Yellow Solid

Molecular weight: 402.45

Ref: 4Z-N-154

Bis(1-methylethyl) 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Controlled Product

CAS: 21881-78-7

Formula: C₂₁H₂₆N₂O₆

Color and Shape: Neat

Molecular weight: 402.44

Ref: 86-MM0416.02

3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine

Controlled Product

CAS: 21881-78-7

Impurity Nimodipine EP Impurity B
Applications 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).
References Avalani, J. R., et al.: J. Chem. Sci., 124, 1091-1096 (2012); Barmpalexis, P., et al.: J. Pharmaceut. Biomed., 49, 1192-1202 (2009)

Formula: C₂₁H₂₆N₂O₆

Color and Shape: Neat

Molecular weight: 402.44

Ref: TR-D291310

(RS)-Di-isopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

CAS: 21881-78-7

Di-isopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is a metabolite of gatifloxacin. It is a natural product and its CAS number is 21881-78-7. Diisopropyl 1,4-dihydro 2,6-dimethyl 4-(3 nitrophenyl) pyridine 3,5 di carboxylate is an impurity standard for gatifloxacin. It has been synthesized and can be custom made to meet the pharmacopeia or API impurity requirements for drug development. The purity of this compound ranges from 98% to 100%. This compound is used in HPLC standards for research and development purposes such as metabolism studies.

Formula: C₂₁H₂₆N₂O₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 402.44 g/mol

Ref: 3D-ID57941

Nimodipine EP Impurity B

CAS: 21881-78-7

Formula: C₂₁H₂₆N₂O₆

Molecular weight: 402.45

Ref: ST-EA-CP-N16002