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CAS 21888-98-2

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Dexetimide

Description:
Dexetimide is a chemical compound classified as an anticholinergic agent, primarily used in the treatment of various conditions related to excessive salivation and as an adjunct in the management of certain gastrointestinal disorders. It functions by blocking the action of acetylcholine at muscarinic receptors, leading to a reduction in secretions and smooth muscle contractions. Dexetimide is characterized by its ability to cross the blood-brain barrier, which may contribute to its central nervous system effects. The compound typically exhibits moderate lipophilicity, influencing its absorption and distribution in the body. Its pharmacokinetic profile includes a relatively short half-life, necessitating careful dosing to maintain therapeutic effects. As with many anticholinergic agents, potential side effects may include dry mouth, blurred vision, constipation, and urinary retention, which arise from its systemic anticholinergic activity. Overall, dexetimide's unique properties make it a valuable option in specific therapeutic contexts, although its use must be carefully monitored to mitigate adverse effects.
Formula:C23H26N2O2
InChI:InChI=1S/C23H26N2O2/c26-21-11-14-23(22(27)24-21,19-9-5-2-6-10-19)20-12-15-25(16-13-20)17-18-7-3-1-4-8-18/h1-10,20H,11-17H2,(H,24,26,27)/t23-/m1/s1
InChI key:InChIKey=LQQIVYSCPWCSSD-HSZRJFAPSA-N
SMILES:O=C1[C@@](CCC(=O)N1)(C2CCN(CC3=CC=CC=C3)CC2)C4=CC=CC=C4
Synonyms:
  • ( )-(R)-3-(1-Benzyl-4-piperidyl)-3-phenyl-2,6-piperidindion
  • (+)-2-(1-Benzyl-4-piperidyl)-2-phenylglutarimide
  • (+)-Benzetimide
  • (3,4'-Bipiperidine)-2,6-dione, 3-phenyl-1'-(phenylmethyl)-, (S)-
  • (3R)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione
  • (3S)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione
  • (3S)-3-Phenyl-1′-(phenylmethyl)[3,4′-bipiperidine]-2,6-dione
  • (S)-(+)-Dexetimide
  • Dexbenzelimid
  • Dexbenzetimide
  • See more synonyms
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