CAS 218926-48-8

2-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]norleucine

Description:

2-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]norleucine is a synthetic compound that belongs to the class of amino acids and derivatives. It features a norleucine backbone, which is an amino acid with a longer carbon chain than leucine, providing unique properties in peptide synthesis and biological activity. The presence of the fluorenylmethoxycarbonyl (Fmoc) group indicates that this compound is likely used in solid-phase peptide synthesis as a protective group for the amino functionality, allowing for selective reactions without interfering with the amine. The butyl side chain contributes to the hydrophobic character of the molecule, which can influence its solubility and interaction with biological membranes. This compound is typically utilized in research and development, particularly in the fields of medicinal chemistry and peptide design, due to its potential applications in drug development and biochemistry. As with many synthetic compounds, handling should be done with care, following appropriate safety protocols to mitigate any risks associated with its use.

Formula: C₂₅H₃₁NO₄

InChI: InChI=1S/C25H31NO4/c1-3-5-15-25(23(27)28,16-6-4-2)26-24(29)30-17-22-20-13-9-7-11-18(20)19-12-8-10-14-21(19)22/h7-14,22H,3-6,15-17H2,1-2H3,(H,26,29)(H,27,28)

InChI key: InChIKey=LFQORNJHCFWMHO-UHFFFAOYSA-N

SMILES: C(OC(NC(CCCC)(CCCC)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• Norleucine, 2-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• 2-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]norleucine

Fmoc-di-n-butylglycine

CAS: 218926-48-8

Fmoc-di-n-butylglycine is a c1-8 alkyl that has been shown to have an antiinflammatory effect. It inhibits the phosphodiesterase enzyme, which is responsible for the degradation of cyclic adenosine monophosphate (cAMP), which increases levels of this molecule. This leads to increased activation of protein kinase A and protein kinase C, which are important in inflammatory pathways. Fmoc-di-n-butylglycine binds to the sodium channel, preventing it from opening and closing, thus inhibiting transmission of electrical signals. This drug has also been shown to inhibit potassium channels and hydrogen sulfate production by bacteria. Fmoc-di-n-butylglycine can be used as a model for the study of other drugs that act on sodium channels.

Formula: C₂₅H₃₁NO₄

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 409.52 g/mol

Ref: 3D-FF49079