CAS 21896-59-3

N-(2-Chloroethyl)methanesulfonamide

Description:

N-(2-Chloroethyl)methanesulfonamide, with the CAS number 21896-59-3, is a chemical compound characterized by its sulfonamide functional group and a chloroethyl substituent. This compound typically appears as a white to off-white solid and is soluble in polar solvents such as water and alcohols, owing to the presence of the sulfonamide group, which enhances its hydrophilicity. It is known for its potential applications in medicinal chemistry, particularly as an intermediate in the synthesis of pharmaceuticals. The chloroethyl moiety can participate in nucleophilic substitution reactions, making it a useful building block in organic synthesis. Additionally, the compound may exhibit biological activity, which is of interest in drug development. Safety considerations are important, as compounds containing chlorine can be reactive and may pose health risks; therefore, proper handling and storage protocols should be followed. Overall, N-(2-Chloroethyl)methanesulfonamide is a versatile compound with significant relevance in both synthetic and medicinal chemistry.

Formula: C₃H₈ClNO₂S

InChI: InChI=1S/C3H8ClNO2S/c1-8(6,7)5-3-2-4/h5H,2-3H2,1H3

InChI key: InChIKey=HLEGMLHPZDVLQL-UHFFFAOYSA-N

SMILES: N(S(C)(=O)=O)CCCl

Synonyms:

• 1-Chloro-2-(methylsulfonamido)ethane
• 2-(Methylsulfonamido)ethyl chloride
• Methanesulfonamide, N-(2-chloroethyl)-
• N-(2-chloroethyl)methanesulfonamide
• β-Methanesulfonamidoethyl chloride
• N-(2-Chloroethyl)methanesulphonamide

N-(2-chloroethyl)methanesulphonamide

CAS: 21896-59-3

Formula: C₃H₈ClNO₂S

Purity: 95%

Color and Shape: Liquid

Molecular weight: 157.6191

Ref: IN-DA003S93

N-(2-Chloroethyl)methanesulfonamide

CAS: 21896-59-3

N-(2-Chloroethyl)methanesulfonamide

Purity: 95%

Molecular weight: 157.62g/mol

Ref: 54-OR94140

N-(2-Chloroethyl)methanesulfonamide

CAS: 21896-59-3

Formula: C₃H₈ClNO₂S

Purity: 95%

Color and Shape: Liquid

Molecular weight: 157.61

Ref: 10-F446202

N-(2-Chloroethyl)methanesulfonamide

CAS: 21896-59-3

N-(2-Chloroethyl)methanesulfonamide (NEMSA) is an ethylene-methanesulfonamide compound that is a serotonergic drug. It has been shown to bind to the 5-HT4 receptor and inhibit the release of serotonin in the brain by blocking chloride channels. NEMSA is used to treat chronic pain, anxiety, and depression. This drug also has affinity for the 5-HT1A receptor and has been shown to be effective in animal models of anxiety and depression. NEMSA binds with high affinity to molecular modeling studies using nitrogen atom as a probe. This drug undergoes a reaction in aqueous solution or reaction system at physiological pH. The pharmacological activity of this drug may be due to its inhibition of serotonin receptors, which are involved in mood regulation, sleep, appetite, sexual function, memory, learning and many other functions.

Formula: C₃H₈ClNO₂S

Purity: Min. 95%

Molecular weight: 157.62 g/mol

Ref: 3D-WAA89659