CAS 2190490-31-2

Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one

CAS: 2190490-31-2

Formula: C₁₉H₁₆ClFN₄O₃

Purity: 98%

Molecular weight: 402.8067

Ref: IN-DA01XG3E

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)

CAS: 2190490-31-2

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)

Purity: 98%

Molecular weight: 402.81g/mol

Ref: 54-PC109942

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)

CAS: 2190490-31-2

Purity: 97%

Molecular weight: 402.81

Ref: 10-F988653

Dacomitinib Impurity 3

CAS: 2190490-31-2

Formula: C₁₉H₁₆ClFN₄O₃

Molecular weight: 402.81

Ref: 4Z-D-212007

Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one

Controlled Product

CAS: 2190490-31-2

Applications Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one is a derivative of Dacomitinib (D101575), which is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.
References Williams, J. et al.: PLoS., 9, e98557 (2014); Peters, S. et al.: Canc. Treatment Rev., 40, 917 (2014);

Formula: C₁₉H₁₆ClFN₄O₃

Color and Shape: Neat

Molecular weight: 402.807

Ref: TR-D101275

Dacomitinib Impurity 1

CAS: 2190490-31-2

Formula: C₁₉H₁₆ClFN₄O₃

Molecular weight: 402.8

Ref: ST-EA-CP-D72003