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CAS 2193-87-5

:

Fluprednidene

Description:
Fluprednidene is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is primarily used in dermatological formulations to treat various skin conditions, including eczema and psoriasis. As a corticosteroid, Fluprednidene functions by inhibiting the release of inflammatory mediators and modulating immune responses, which helps reduce redness, swelling, and itching associated with inflammatory skin disorders. The substance is characterized by its potent glucocorticoid activity, which is significantly higher than that of many other corticosteroids, allowing for effective treatment at lower doses. Fluprednidene is typically available in topical formulations, such as creams or ointments, and is applied directly to the affected area. While it is effective in managing symptoms, prolonged use can lead to potential side effects, including skin thinning and systemic absorption, particularly if used over large areas or under occlusive dressings. Therefore, it is essential to use Fluprednidene under medical supervision to minimize risks and ensure appropriate therapeutic outcomes.
Formula:C22H27FO5
InChI:InChI=1S/C22H27FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,15-17,24,26,28H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17-,19-,20-,21-,22-/m0/s1
InChI key:InChIKey=YVHXHNGGPURVOS-SBTDHBFYSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)C(=C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:
  • (11β)-9-Fluoro-11,17,21-trihydroxy-16-methylenepregna-1,4-diene-3,20-dione
  • 9-Alpha-Fluoro-11-Beta,17-Alpha,21-Trihydroxy-16-Methylenepregna-1,4-Diene-3,20-Dione
  • 9-Fluoro-11,17,21-Trihydroxy-16-Methylidenepregna-1,4-Diene-3,20-Dione
  • 9-Fluoro-16-methyleneprednisolone
  • 9α-Fluoro-16-methyleneprednisolone
  • Fluprednidene Acetate
  • Fluprednylidene
  • Fluprednylidene-21-ol
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methylene-, (11β)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16-methylene-
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Found 3 products.
  • Fluprednidene
    TLC
    + Info

    Fluprednidene

    CAS:
    Formula:C22H27FO5
    Molecular weight:390.45

    Ref: 4Z-F-193005

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • Fluprednidene
    TRC
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    Fluprednidene

    Controlled Product
    CAS:

    Applications Fluprednidene is obtained from Fluprednidene Acetate (F598600) which is a Anti-inflammatory (topical).
    References Werder, et al.: Arzneim.-Forsch., 18, 7 (1968);

    Formula:C22H27FO5
    Color and Shape:Neat
    Molecular weight:390.445

    Ref: TR-F598595

    100mg
    8,806.00€
  • (11b)-9-Fluoro-11,17,21-trihydroxy-16-methylene-Pregna-1,4-diene-3,20-dione
    Biosynth
    + Info

    (11b)-9-Fluoro-11,17,21-trihydroxy-16-methylene-Pregna-1,4-diene-3,20-dione

    Controlled Product
    CAS:
    (11b)-9-Fluoro-11,17,21-trihydroxy-16-methylene-Pregna-1,4-diene-3,20-dione is a corticosteroid that binds to glucocorticoid receptors in the cells of various tissues. It is used for the treatment of inflammatory bowel disease and other autoimmune diseases. It has been shown to inhibit the growth of certain bacteria by disrupting the cell membrane and inhibiting protein synthesis. This drug also has anti-inflammatory properties, which may be due to its ability to induce apoptosis in certain cells. The use of this drug is not recommended for people with a history of skin cancer or who have any form of active cancer.
    Formula:C22H27FO5
    Purity:Min. 95%
    Molecular weight:390.45 g/mol

    Ref: 3D-FF99757

    175mg
    To inquire