CAS 21940-45-4

6-Dehydrocortisol Acetate

Description:

6-Dehydrocortisol acetate is a synthetic derivative of cortisol, a steroid hormone produced by the adrenal glands. This compound is characterized by its structural modifications that enhance its pharmacological properties. It typically exhibits anti-inflammatory and immunosuppressive effects, making it relevant in therapeutic applications, particularly in treating conditions like autoimmune disorders and allergies. The acetate group in its structure contributes to its solubility and stability, facilitating its use in various formulations. As a glucocorticoid, 6-dehydrocortisol acetate interacts with glucocorticoid receptors, influencing gene expression and cellular responses. Its pharmacokinetics may involve metabolism in the liver, with potential conversion to active or inactive metabolites. Safety and efficacy profiles are essential considerations in its use, as with other corticosteroids, to mitigate potential side effects such as adrenal suppression or metabolic disturbances. Overall, 6-dehydrocortisol acetate represents a significant compound in the realm of synthetic corticosteroids, with applications in clinical settings requiring careful management and monitoring.

Formula: C₂₃H₃₀O₆

Synonyms:

• Δ6-hydrocortisone-21-acetate
• Pregna-4,6-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11β)- (9CI)
• 11beta,17,21-Trihydroxypregna-4,6-d
• 11β,17,21-Trihydroxypregna-4,6-diene-3,20-dione 21-Acetate
• 6-Dehydrocortisol Acetate

6-Dehydro Hydrocortisone Acetate

CAS: 21940-45-4

Formula: C₂₃H₃₀O₆

Molecular weight: 402.49

Ref: 4Z-H-103018

11β,17,21-Trihydroxypregna-4,6-diene-3,20-dione 21-Acetate

Controlled Product

CAS: 21940-45-4

Formula: C₂₃H₃₀O₆

Color and Shape: Neat

Molecular weight: 402.48

Ref: 86-MM0187.09

6-Dehydrocortisol Acetate

Controlled Product

CAS: 21940-45-4

Applications 6-Dehydrocortisol Acetate, an acetylated derivative of 6-Dehydrocortisol (D229145), is a substituted corticosteroid with antiinflammatory activity.
References Green, M. et al.: J. Steroid. Biochem., 6, 599 (1975)

Formula: C₂₃H₃₀O₆

Color and Shape: Neat

Molecular weight: 402.48

Ref: TR-D229225

6-Dehydrocortisol Acetate

CAS: 21940-45-4

Formula: C₂₃H₃₀O₆

Molecular weight: 402.5

Ref: ST-EA-CP-H9100