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CAS 219685-50-4

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Immunoglobulin,anti-(human complement C5 a-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide withhuman-mouse monoclonal 5G1.1 light chain, dimer (9CI)

Description:
Immunoglobulin, anti-(human complement C5 a-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide with human-mouse monoclonal 5G1.1 light chain, dimer (CAS 219685-50-4) is a monoclonal antibody designed to target the human complement component C5a, which plays a crucial role in the immune response and inflammation. This antibody is a chimeric molecule, combining elements from both human and mouse immunoglobulins, which enhances its specificity and reduces immunogenicity when used in therapeutic applications. The structure consists of two heavy chains and two light chains linked by disulfide bonds, forming a dimeric configuration that is typical for antibodies. Its primary characteristics include high affinity for the C5a antigen, which allows it to effectively inhibit the biological activity of C5a, potentially mitigating inflammatory responses. This monoclonal antibody is utilized in research and clinical settings, particularly in studies related to complement-mediated diseases and therapeutic interventions aimed at modulating immune responses.
Synonyms:
  • Eculizumab
  • Soliris
  • h5G1.1
  • h5G1.1VHC+h5G1.1VLC
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