CAS 219706-48-6

bromo-(3-ethoxyphenyl)magnesium

Description:

Bromo-(3-ethoxyphenyl)magnesium, with the CAS number 219706-48-6, is an organomagnesium compound that belongs to the class of Grignard reagents. These reagents are characterized by their highly reactive nature, particularly towards electrophiles, making them valuable in organic synthesis. The compound features a bromo substituent attached to a 3-ethoxyphenyl group, which enhances its reactivity due to the presence of the electron-donating ethoxy group. This structure allows for nucleophilic attack on carbonyl compounds, enabling the formation of alcohols upon hydrolysis. The compound is typically prepared by reacting magnesium with the corresponding bromo-aryl compound in anhydrous ether or similar solvents, under inert atmosphere conditions to prevent moisture interference. As with other Grignard reagents, bromo-(3-ethoxyphenyl)magnesium must be handled with care, as it reacts vigorously with water and air, releasing flammable gases and potentially leading to hazardous situations. Its applications in synthetic organic chemistry include the formation of carbon-carbon bonds and the synthesis of complex organic molecules.

Formula: C₈H₉BrMgO

InChI: InChI=1/C8H9O.BrH.Mg/c1-2-9-8-6-4-3-5-7-8;;/h3-4,6-7H,2H2,1H3;1H;/q;;+1/p-1/rC8H9BrMgO/c1-2-11-8-5-3-4-7(6-8)10-9/h3-6H,2H2,1H3

SMILES: CCOc1ccccc1.Br.[Mg]

Synonyms:

• 3-Ethoxyphenylmagnesium bromide solution
• 3-Ethoxyphenylmagnesium bromide, 0.5 M in THF
• 3-ETHOXYPHENYLMAGNESIUM BROMIDE