The chemical substance known as Pyrimidine, 2-(3,5-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl]- is a complex organic compound characterized by its pyrimidine core structure, which is a six-membered ring containing two nitrogen atoms at positions 1 and 3. This compound features a phenoxy group substituted at the 2-position of the pyrimidine ring, along with a 4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl moiety at the 4-position. The presence of the dimethylphenyl group contributes to its hydrophobic characteristics, while the fluorophenyl and piperidinyl groups may enhance its biological activity and solubility properties. This compound is likely to exhibit significant pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its specific interactions and mechanisms of action would depend on its structural features and the presence of functional groups, which can influence binding affinity and selectivity for biological targets.

Pyrimidine, 2-(3,5-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl]-

219769-23-0: The chemical substance known as Pyrimidine, 2-(3,5-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl]- is a complex organic compound characterized by its pyrimidine core structure, which is a six-membered ring containing two nitrogen atoms at positions 1 and 3. This compound features a phenoxy group substituted at the 2-position of the pyrimidine ring, along with a 4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl moiety at the 4-position. The presence of the dimethylphenyl group contributes to its hydrophobic characteristics, while the fluorophenyl and piperidinyl groups may enhance its biological activity and solubility properties. This compound is likely to exhibit significant pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its specific interactions and mechanisms of action would depend on its structural features and the presence of functional groups, which can influence binding affinity and selectivity for biological targets.

<p>SB-284851-BT: BRD4/p38α/BRDT inhibitor; IC50: BRD4-BD1 1.7µM, BRDT 18µM, BRD4 3.7µM; Kd p38α 0.47nM; reduces IL-8, affects c-Myc/NF-κB.</p>

CAS 219769-23-0

Pyrimidine, 2-(3,5-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl]-

SB-284851-BT

Ref: TM-T69815