NLRP3-IN-29, with the CAS number 2198483-40-6, is a small molecule inhibitor specifically designed to target the NLRP3 inflammasome, a critical component of the innate immune system involved in inflammatory responses. This compound is characterized by its ability to modulate the activation of NLRP3, thereby potentially reducing the production of pro-inflammatory cytokines such as IL-1β and IL-18. NLRP3-IN-29 is of particular interest in research related to various inflammatory diseases, including autoimmune disorders, metabolic syndromes, and neurodegenerative conditions. Its chemical structure typically includes functional groups that enhance its binding affinity to the NLRP3 protein, promoting its inhibitory action. The compound is usually evaluated for its efficacy and safety through in vitro and in vivo studies, contributing to the understanding of its therapeutic potential. As research progresses, NLRP3-IN-29 may pave the way for novel treatments targeting NLRP3-related pathologies.

NLRP3-IN-29

2198483-40-6: NLRP3-IN-29, with the CAS number 2198483-40-6, is a small molecule inhibitor specifically designed to target the NLRP3 inflammasome, a critical component of the innate immune system involved in inflammatory responses. This compound is characterized by its ability to modulate the activation of NLRP3, thereby potentially reducing the production of pro-inflammatory cytokines such as IL-1β and IL-18. NLRP3-IN-29 is of particular interest in research related to various inflammatory diseases, including autoimmune disorders, metabolic syndromes, and neurodegenerative conditions. Its chemical structure typically includes functional groups that enhance its binding affinity to the NLRP3 protein, promoting its inhibitory action. The compound is usually evaluated for its efficacy and safety through in vitro and in vivo studies, contributing to the understanding of its therapeutic potential. As research progresses, NLRP3-IN-29 may pave the way for novel treatments targeting NLRP3-related pathologies.

<p>NLRP3-IN-29 (Compound 5M) is an inhibitor of NLR family pyrin domain containing 3 (NLRP3) with potential for blood-brain barrier permeability and inflammation inhibition both in vivo and in vitro. It can be used for research on Alzheimer's disease [1].</p>

CAS 2198483-40-6

NLRP3-IN-29

NLRP3-IN-29

Ref: TM-T87020