CAS 2200269-28-7

(αR)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-2-naphthalenemethanamine Hydrochloride

Description:

(αR)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-2-naphthalenemethanamine Hydrochloride, identified by its CAS number 2200269-28-7, is a chemical compound characterized by its complex structure, which includes a naphthalene moiety and a trifluoromethyl-substituted phenyl group. This compound is typically classified as an amine due to the presence of an amine functional group, which contributes to its potential biological activity. The hydrochloride salt form indicates that it is a hydrochloride, which often enhances solubility in water and stability. The presence of the trifluoromethyl group suggests that it may exhibit unique electronic properties, potentially influencing its reactivity and interactions with biological targets. Such compounds are often investigated for their pharmacological properties, including potential applications in medicinal chemistry. Overall, the specific stereochemistry indicated by the (αR) designation suggests that the compound may exhibit chiral properties, which can significantly affect its biological activity and interactions.

Formula: C₂₂H₂₃ClF₃N

Synonyms:

• (αR)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-2-naphthalenemethanamine Hydrochloride
• (aR)-a-Methyl-N-[3-[3-(trifluoromethyl)phenyl]Propyl]-2-naphthalenemethan amine hydrochloride
• Cinacalcet Impurity 24 HCl
• Cinacalcet Impurity 1 HCl

Cinacalcet Impurity 10 HCl

CAS: 2200269-28-7

Formula: C₂₂H₂₂F₃N·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 357.42 36.46

Ref: 4Z-C-4017

(AlphaR)-Alpha-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-2-naphthalenemethanamine Hydrochloride

Controlled Product

CAS: 2200269-28-7

Applications (αR)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-2-naphthalenemethanamine Hydrochloride is an impurity of Cinacalcet (C441800), which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels).
References Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003), Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004),

Formula: C₂₂H₂₂F₃N·HCl

Color and Shape: Neat

Molecular weight: 393.9

Ref: TR-M331105

Cinacalcet regio isomer

CAS: 2200269-28-7

Formula: C₂₂H₂₂F₃NHCl

Molecular weight: 357.4 : 36.5

Ref: ST-EA-CP-C21010

N-[1-(R)-(+)-(2-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride

CAS: 2200269-28-7

N-[1-(R)-(+)-(2-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride is a metabolite that is produced by the metabolism of naphthalene. It is an impurity in the naphthalene standard, which is used as an API to assess the purity of other substances. N-[1-(R)-(+)-(2-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride has been shown to be a substrate for CYP2D6. This metabolite is also found in pharmaceuticals and other drugs.

Formula: C₂₂H₂₂F₃N•HCl

Purity: Min. 95%

Molecular weight: 393.87 g/mol

Ref: 3D-IN58182