CAS 22006-64-0

adrenocorticotropic hormone fragment*1-13

Description:

Adrenocorticotropic hormone fragment 1-13, associated with the CAS number 22006-64-0, is a peptide derived from the larger adrenocorticotropic hormone (ACTH), which plays a crucial role in the regulation of cortisol production from the adrenal glands. This specific fragment consists of the first 13 amino acids of the ACTH molecule, retaining some of the biological activity of the full-length hormone. Characteristically, it is a small peptide that exhibits hydrophilic properties, which influence its solubility in aqueous solutions. The fragment is involved in various physiological processes, including stress response and metabolism regulation. Its structure allows it to interact with specific receptors, potentially influencing adrenal function and other related pathways. In research and therapeutic contexts, this fragment may be studied for its role in endocrine signaling and its potential implications in conditions related to adrenal function. Overall, the fragment serves as a valuable tool for understanding the biological functions of ACTH and its derivatives.

Formula: C₇₅H₁₀₆N₂₀O₁₉S

InChI: InChI=1/C75H106N20O19S/c1-41(2)62(74(113)114)94-72(111)59-19-12-29-95(59)73(112)53(17-9-10-27-76)85-60(99)37-83-64(103)56(33-44-35-82-49-16-8-7-15-47(44)49)91-65(104)50(18-11-28-81-75(78)79)86-68(107)55(31-42-13-5-4-6-14-42)90-70(109)57(34-45-36-80-40-84-45)92-66(105)51(24-25-61(100)101)87-67(106)52(26-30-115-3)88-71(110)58(39-97)93-69(108)54(89-63(102)48(77)38-96)32-43-20-22-46(98)23-21-43/h4-8,13-16,20-23,35-36,40-41,48,50-59,62,82,96-98H,9-12,17-19,24-34,37-39,76-77H2,1-3H3,(H,80,84)(H,83,103)(H,85,99)(H,86,107)(H,87,106)(H,88,110)(H,89,102)(H,90,109)(H,91,104)(H,92,105)(H,93,108)(H,94,111)(H,100,101)(H,113,114)(H4,78,79,81)/t48-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1

SMILES: CC(C)[C@@H](C(=O)O)N=C([C@@H]1CCCN1C(=O)[C@H](CCCCN)N=C(CN=C([C@H](Cc1c[nH]c2ccccc12)N=C([C@H](CCCNC(=N)N)N=C([C@H](Cc1ccccc1)N=C([C@H](Cc1cnc[nH]1)N=C([C@H](CCC(=O)O)N=C([C@H](CCSC)N=C([C@H](CO)N=C([C@H](Cc1ccc(cc1)O)N=C([C@H](CO)N)O)O)O)O)O)O)O)O)O)O)O

Synonyms:

• Tridecactide [INN]
• Acth (1-13)
• (Des-acetyl)-alpha-MSH
• Adrenocorticotropin (1-13)NH2
• DE-alpha-Msh
• Des-acetyl MSH
• Desacetyl alpha-melanocyte-stimulating hormone
• MSH, (desacetyl)alpha-
• Tridecactide
• alpha1-13-Corticotropin
• alpha-1-13-corticotropin, humanL-seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valine
• L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valine

ACTH (1-13)

CAS: 22006-64-0

ACTH (1–13) is a fragment of the ACTH hormone, which stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. ACTH (1–13) is an agonist of the melanocortin-3 receptor.

Formula: C₇₅H₁₀₆N₂₀O₁₉S

Purity: 98.4%

Color and Shape: White Powder

Molecular weight: 1623.86

Ref: 01-4014703

ACTH (1-13)

CAS: 22006-64-0

ACTH (1-13), a 13-amino acid peptide, protects rats' stomachs from ethanol damage; it’s a stress-response hormone from the pituitary.

Formula: C₇₅H₁₀₆N₂₀O₁₉S

Purity: 98%

Color and Shape: Solid

Molecular weight: 1623.83

Ref: TM-TP1247

ACTH (1-13), human

CAS: 22006-64-0

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₇₅H₁₀₆N₂₀O₁₉S

Molecular weight: 1,623.9 g/mol

Ref: 3D-PP50327

ACTH (1-13), human

CAS: 22006-64-0

Custom research peptide; min purity 95%.

Formula: C₇₅H₁₀₆N₂₀O₁₉S

Purity: Min. 95%

Molecular weight: 1,623.9 g/mol

Ref: 3D-PA16893