CAS 220088-40-4

[METHYL-D3]METANICOTINE

Description:

[Methyl-D3]metanicotine, with the CAS number 220088-40-4, is a deuterated analog of metanicotine, which is a compound related to nicotine. Deuteration involves the substitution of hydrogen atoms with deuterium, a heavier isotope of hydrogen, which can influence the compound's physical and chemical properties. This substance is characterized by its molecular structure, which includes a pyridine ring and a methyl group, contributing to its potential biological activity. The presence of deuterium can enhance the stability of the compound and alter its metabolic pathways, making it useful in pharmacological studies and research on nicotine's effects. Typically, deuterated compounds are employed in various applications, including tracer studies in metabolic research and as standards in analytical chemistry. The specific characteristics, such as solubility, boiling point, and reactivity, would depend on the overall molecular structure and the presence of functional groups, but detailed data would be necessary for precise values.

Formula: C₁₀H₁₁D₃N₂

Synonyms:

• [METHYL-D3]RJR2403
• [METHYL-D3]METANICOTINE
• Methyl Metanicotine-d3
• (E)-Metanicotine-d3
• (E)-N-[Methyl-d3]-4-(3-pyridinyl)-3-buten-1-amine, [Methyl-d3]RJR2403
• Rivanicline-d3
• (E)-N-[METHYL-D3]-4-(3-PYRIDINYL)-3-BUTEN-1-AMINE

Metanicotine-d3

Controlled Product

CAS: 220088-40-4

Applications Metanicotine-d3 is the isotope labelled analog of Metanicotine (M321250); an alkaloid found in the leaves of Duboisia Hopwoodii and a constitutent of tobacco smoke. Also used as a potential drug for the treatment of senile dementia of the Alzheimer’s type, and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to peripheral ganglionic and muscle-type nicotinic acetylcholine receptors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schmeltz, I., et al.: J. Sci. Food Agric., 15, 744 (1964); Griffin, W.J. and Luanratana, O.: Phytochemistry, 21, 499 (1982); Jacob III, P., et al.: J. Chromatogr., 619, 49 (1993); Lippiello, P.M., et al.: J. Pharm. Exp. Therap., 279, 1422 (1996)

Formula: C₁₀₂H₃H₁₁N₂

Color and Shape: Neat

Molecular weight: 165.25

Ref: TR-M321252