Description:5-Fluoroorotic acid monohydrate is a chemical compound that serves as a derivative of orotic acid, characterized by the substitution of a fluorine atom at the 5-position of the pyrimidine ring. This modification imparts unique properties, making it of interest in various biochemical and pharmaceutical applications. The monohydrate form indicates the presence of one molecule of water associated with each molecule of the acid, which can influence its solubility and stability. Typically, 5-fluoroorotic acid exhibits moderate solubility in water and is often utilized in research related to nucleic acid metabolism and as a potential therapeutic agent in cancer treatment due to its ability to interfere with pyrimidine metabolism. Its mechanism of action may involve the inhibition of specific enzymes involved in nucleotide synthesis. As with many fluorinated compounds, it may also exhibit distinct biological activities and toxicity profiles, necessitating careful handling and study in laboratory settings. Overall, 5-fluoroorotic acid monohydrate is a compound of significant interest in medicinal chemistry and biochemistry.
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