CAS 2203-97-6

Hydrocortisone hemisuccinate

Description:

Hydrocortisone hemisuccinate is a synthetic derivative of hydrocortisone, classified as a corticosteroid. It is primarily used for its anti-inflammatory and immunosuppressive properties. The substance is characterized by its esterification of hydrocortisone with succinic acid, which enhances its solubility and bioavailability, making it suitable for parenteral administration. Hydrocortisone hemisuccinate exhibits a white to off-white crystalline appearance and is typically soluble in water and alcohol, facilitating its use in various pharmaceutical formulations. Its mechanism of action involves the modulation of gene expression and inhibition of pro-inflammatory cytokines, thereby reducing inflammation and immune responses. This compound is often utilized in clinical settings for the treatment of conditions such as adrenal insufficiency, allergic reactions, and certain autoimmune disorders. As with other corticosteroids, it may have side effects, including potential impacts on metabolism, immune function, and electrolyte balance, necessitating careful monitoring during therapy. Overall, hydrocortisone hemisuccinate serves as an important therapeutic agent in managing inflammatory and autoimmune conditions.

Formula: C₂₅H₃₄O₈

InChI: InChI=1S/C25H34O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1

InChI key: InChIKey=VWQWXZAWFPZJDA-CGVGKPPMSA-N

SMILES: C[C@@]12[C@]([C@]3([C@]([C@@H](O)C1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(CC[C@@]2(C(COC(CCC(O)=O)=O)=O)O)[H]

Synonyms:

• (11β)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxypregn-4-ene-3,20-dione
• 11b,17a,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate
• 4-{[(11Beta)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl]Oxy}-4-Oxobutanoic Acid
• 4-{[(8Xi,9Xi,11Beta,14Xi)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl]Oxy}-4-Oxobutanoic Acid
• Cortisol 21-hemisuccinate
• Cortisol hemisuccinate
• Cortisol succinate
• Cortisol, 21-(hydrogen succinate)
• Cortisol, hydrogen succinate
• Hydrocortisone 21-(Hydrogen Succinate)
• Hydrocortisone 21-O-β-carbonylpropionic acid
• Hydrocortisone 21-hemisuccinate
• Hydrocortisone 21-succinate
• Hydrocortisone Hemisuccinate
• Hydrocortisone Succinate
• Hydrocortisone hydrogen succinate
• NSC 7576
• Pregn-4-ene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11β)-
• Saxizon

Hydrocortisone Hemisuccinate

CAS: 2203-97-6

Formula: C₂₅H₃₄O₈

Molecular weight: 462.54

Ref: ST-EA-CP-H9042

Hydrocortisone hydrogen succinate

CAS: 2203-97-6

Hydrocortisone hydrogen succinate

Formula: C₂₅H₃₄O₈

Color and Shape: White

Molecular weight: 462.5327

Ref: 47-187

Pregn-4-ene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11b)-

CAS: 2203-97-6

Formula: C₂₅H₃₄O₈

Purity: 95%

Color and Shape: Solid

Molecular weight: 462.5327

Ref: IN-DA00I4AZ

Hydrocortisone hemisuccinate

CAS: 2203-97-6

Hydrocortisone hemisuccinate

Purity: ≥98%

Molecular weight: 462.53g/mol

Ref: 54-BUP13714

Hydrocortisone hemisuccinate

CAS: 2203-97-6

Formula: C₂₅H₃₄O₈

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 462.53

Ref: 7W-GP1580

Hydrocortisone-21-Succinate

CAS: 2203-97-6

Formula: C₂₅H₃₄O₈

Molecular weight: 462.54

Ref: 4Z-H-103048

Hydrocortisone Hydrogen Succinate

Controlled Product

CAS: 2203-97-6

Formula: C₂₅H₃₄O₈

Color and Shape: Neat

Molecular weight: 462.53

Ref: 86-MM0275.00

Hydrocortisone hemisuccinate (Standard)

CAS: 2203-97-6

Hydrocortisone hemisuccinate (Standard) is the standard substance of Hydrocortisone hemisuccinate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.

Formula: C₂₅H₃₄O₈

Molecular weight: 462.53

Ref: TM-TMSM-1331

Hydrocortisone 21-Hemisuccinate

CAS: 2203-97-6

Formula: C₂₅H₃₄O₈

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 462.54

Ref: 3B-H1884

Hydrocortisone Sodium Succinate

Controlled Product

CAS: 125-04-2, 2203-97-6

Formula: C₂₅H₃₄O₈

Color and Shape: Neat

Molecular weight: 462.53

Ref: 86-MM3100.00

Hydrocortisone hemisuccinate

CAS: 2203-97-6

Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.

Formula: C₂₅H₃₄O₈

Purity: 98.01% - 98.7%

Color and Shape: Solid

Molecular weight: 462.53

Ref: TM-T4602

Hydrocortisone Succinate RS

CAS: 2203-97-6

Color and Shape: White Solid Crystalline Powder

Ref: 2K-1121000021

Hydrocortisone 21-Hemisuccinate

Controlled Product

CAS: 2203-97-6

Applications Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
References Eur. Pat. Appl. (1985), EP 156643 A2 19851002.

Formula: C₂₅H₃₄O₈

Color and Shape: Neat

Molecular weight: 462.53

Ref: TR-H716563

Hydrocortisone 21-hemisuccinate

Controlled Product

CAS: 2203-97-6

Hydrocortisone 21-hemisuccinate is a synthetic corticosteroid, which is a derivative of the naturally occurring steroid hormone cortisol. It is produced through chemical synthesis in pharmaceutical laboratories and designed to enhance water solubility and ease of administration. This compound exerts its effects by mimicking the activity of endogenous corticosteroids, primarily through binding to glucocorticoid receptors. Once bound, it modulates gene expression, leading to anti-inflammatory and immunosuppressive actions.

Formula: C₂₅H₃₄O₈

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 462.53 g/mol

Ref: 3D-FH44457