CAS 220556-69-4

ACEA

Description:

ACEA, with the CAS number 220556-69-4, is a chemical compound that belongs to the class of small molecules often studied for their potential biological activities. While specific characteristics such as its molecular formula, structure, and physical properties may vary, compounds like ACEA are typically characterized by their interactions with biological targets, which may include receptors or enzymes. ACEA is known to exhibit specific pharmacological effects, making it of interest in medicinal chemistry and drug development. Its solubility, stability, and reactivity can be influenced by various factors, including pH and temperature. Additionally, ACEA may undergo metabolic transformations in biological systems, which can affect its efficacy and safety profile. Researchers often investigate its mechanism of action, potential therapeutic applications, and any associated toxicity. Overall, ACEA represents a class of compounds that are valuable in the exploration of new therapeutic avenues in pharmacology.

Formula: C₂₂H₃₆ClNO

InChI: InChI=1S/C22H36ClNO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-

InChI key: InChIKey=SCJNCDSAIRBRIA-DOFZRALJSA-N

SMILES: C(C/C=C\C/C=C\C/C=C\C/C=C\CCCCC)CC(NCCCl)=O

Synonyms:

• (5Z,8Z,11Z,14Z)-N-(2-Chloroethyl)-5,8,11,14-eicosatetraenamide
• Acea
• Arachidonyl-2-chloroethylamide
• 5,8,11,14-Eicosatetraenamide, N-(2-chloroethyl)-, (5Z,8Z,11Z,14Z)-

Arachidonyl-2-chloroethylamide

CAS: 220556-69-4

Formula: C₂₂H₃₆ClNO

Purity: >98.0%(HPLC)

Color and Shape: Colorless to Brown clear liquid

Molecular weight: 365.99

Ref: 3B-A3445

Arachidonyl-2''-chloroethylamide hydrate

CAS: 220556-69-4

Formula: C₂₂H₃₆ClNO·xH₂O

Purity: ≥ 97.0%

Color and Shape: Colourless oil

Molecular weight: 365.98 (anhydrous)

Ref: 7W-GK5286

ACEA

CAS: 220556-69-4

ACEA

Purity: 96%

Molecular weight: 365.98g/mol

Ref: 54-OR1034731

Arachidonyl-2-chloroethylamide

Controlled Product

CAS: 220556-69-4

Applications Arachidonyl-2-chloroethylamide is a synthetic cannabinoid receptor 1 (CB1R) and cannabinoid receptor 2 (CB2R) agonist (1,2). It exhibits higher affinity for CB1R than CB2R.
References (1) Hillard, C.J. et al.: J. Pharmacol. Exp. Therap., 289, 1427 (1999) (2) Luszczki, J.J. et al.: Prog Neuropsychopharmacol Biol Psychiatry. 34, 18 (2010)

Formula: C₂₂H₃₆ClNO

Color and Shape: Neat

Molecular weight: 365.98

Ref: TR-A765020

ACEA, 5mg/ml solution in ethanol

CAS: 220556-69-4

Cannabinoid type 1 (CB1) receptor agonist. Anti-depressant activity demonstrated in vivo alone, as well as enhancing the effect of fluoxetine. In the brain, ACEA activates CB1 receptors expressed in the mitochondria of neuronal cells to elicit neuroprotective effects. This is mediated by inducing glycogen synthase kinase-3β (GSK-3β) phosphorylation and inhibiting the opening of mitochondrial permeability transition pore (MPTP).
Sold by weight of solid

Formula: C₂₂H₃₆ClNO

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 365.98 g/mol

Ref: 3D-BA17966

ACEA

CAS: 220556-69-4

ACEA is a selective CB1 agonist with Ki of 1.4 nM for CB1 and >2,000 nM for CB2, induces hypothermia in mice, and may be metabolized by FAAH.

Formula: C₂₂H₃₆ClNO

Color and Shape: Solid

Molecular weight: 365.98

Ref: TM-T38138